Adrenal insufficiency and miscellaneous Flashcards
What is Addison’s disease?
absent/low glucocorticoid and/or mineralcorticoid
etiologies of adrenal insufficiency
autoimmune reaction (MCC in developed countries; AAb’s to 21-hydroxylase)
adrenal hemorrhage
tuberculosis (MCC in developing countries
infections
steroid withdrawal
post-adrenalectomy
tx of adrenal insufficiency?
hydrocortisone 100mg q8h
fludrocortisone 0.1 mg qDay
sx’s of adrenal insufficiency?
HypoT unresponsive to fluids
Severe abdominal pain
What is a benign adrenal adenoma composed of bone marrow and adipose elements?
Myelolipoma
- don’t confuse with angiomyolipoma, which is exclusively in the kidney
what is Sheehans syndrome?
post-partum hypopituitarism secondary to necrosis/hypoperfusion
2 causes of waterhouse-friderichsen syndrome?
hemorrhagic adrenalitis
N. meningitidis