Adrenal Disorders Flashcards

1
Q

What is a disorder where adrenal glands don’t produce enough glucorticoid hormones?

A

Addison’s Disease

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2
Q

What is a condition from exposure to high cortisol levels for a long period of time?

A

Cushing’s Disease

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3
Q

What secretes cortisol?

A

Adrenal glands

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4
Q

What is cortisol?

A

Stress hormone

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5
Q

Name this disorder: Moon face (very round face) buffalo hump (fat deposits b/t shoulder blades), thin skin, unhealed wounds, fine coating of hair on face/body, abd striae, ecchymosis, pear shaped body?

A

Cushing’s Disease

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6
Q

Normal calcium levels?

A

8.5-10.2

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7
Q

Cortisol levels blood, urine, saliva are taken when?

A

@ diff times to evaluate variations

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8
Q

What may be increased in Cushing’s disease?

A

Sodium and glucose level

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9
Q

What may be decreased in Cushing’s disease?

A

Potassium and calcium levels

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10
Q

What diagnostic tests for Cushing’s looks for lesions of adrenal or pituitary gland?

A

CT/MRI/Xray

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11
Q

What is a normal level of cortisol in the urine?

A

80-100mcg

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12
Q

Name this disorder: elevated BP, bounding pulses, sodium/water retention, hypervolemia, edema, muscle atrophy, osteoporosis, elevated blood glucose, immunosuppression, increased risk for infection and emotional instability?

A

Cushing’s Disease

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13
Q

Bilateral adrenal hyperplasia, pituitary adenoma, carcinomas of lung/GI/pancreas and adrenal adenoma or carcinoma is indicative of?

A

Cushing’s Disease

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14
Q

Therapeutic over use of glucosteroids in asthma, autoimmune disorders, chemo, allergic responses, or chronic fibrosis is indicative of what?

A

Cushing’s syndrome

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15
Q

What surgical procedures are commonly used for Cushing’s Disease?

A

Hypophysectomy and adrenalectomy

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16
Q

What is hypophysectomy?

A

Removal of pituitary gland

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17
Q

What is adrenalectomy?

A

Partial/complete removal of adrenal gland

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18
Q

What is the halo sign that is tested after surgical procedures?

A

Yellow halo look around blood discharge from nose; positive for CSF

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19
Q

How can a pt. know that they have CSF leak?

A

If salty taste leaks into mouth

20
Q

What should a pt avoid if have a CSF leak?

A

Blowing nose, driving and bending if pain/numbness in mouth rinse w/ saline for 2wks

21
Q

Which med is used in Cushing’s syndrome?

A

Aminogluthethimide (Cytadren)

22
Q

What are some side effects of aminogluthethimide (Cytadren)?

A

Med failure, nausea, dizziness, skin rash, liver toxicity, jaundice, skin lesions

23
Q

What are some nursing implications for aminogluthethimide (Cytadren)?

A

Take w/ food and monitor liver function tests

24
Q

What is the drug of choice for Cushing’s?

A

Ketoconazole

25
Q

What is another med for Cushing’s?

A

Spironlactone (Aldactone)

26
Q

What is Spironlactone (Aldactone)?

A

Aldosterone antagonist, blocks resorption of water and sodium

27
Q

When is Spironlactone (Aldactone) used?

A

When adrenal hyperplasia is the cause

28
Q

What are side effects of Spironlactone (Aldactone)?

A

Dizziness, HA, diarrhea, urinary frequency, increase potassium

29
Q

What are some nursing implications for Spironlactone (Aldactone)?

A

Monitor vs/wt/Na/K levels

30
Q

What is needed w/ Spironlactone (Aldactone)?

A

Potassium sparing diuretic

31
Q

What are the nursing implications for fluid overload in Cushing’s?

A

Monitor Wt, I/O, and VS assess for edema (especially in sacrum), assess breath sounds (crackles/rales/wheezes) and put on fluid restrictions

32
Q

What are the nursing implications for risk for infection in Cushing’s?

A

Monitor VS/labs, use aseptic technique, increase protein and vitamins

33
Q

What are the nursing implications for knowledge deficit in Cushing’s?

A

Education on med regimen (don’t stop abruptly), diet restrictions (no alcohol/caffeine), daily wts, and s/s of infections

34
Q

Autoimmune disorder, HIV/TB, Hemorrhage, infection, tumors, adrenalectomy, and sudden withdrawal of long-term, high dose glucocorticoid therapy are all causes of what?

A

Not enough production of glucocorticoid (Addison’s)

35
Q

Lack of adrenocorticotropic hormone doesn’t stimulate enough what?

A

Cortisol

36
Q

Name this disorder: diet change, increased appetite for salt, weakness/fatigue, dehydration s/s, N/V, anorexia, hyperpigmentation (90% bronze color), orthostatic hypotension and mood changes?

A

Addison’s

37
Q

What levels are high in Addison’s?

A

BUN, Potassium and calcium

38
Q

What levels are low in Addison’s?

A

Cortisol, Glucose and sodium

39
Q

ACTH Stim test, CT/MRI are what?

A

Diagnostic tests to evaluate adrenal/pituitary glands

40
Q

What is the combo pharmacology for Addison’s?

A

Mineralocorticoid (Florinef) and Glucocorticoid (Prednsione)

41
Q

What are some adverse effects of Mineralcorticoid (Florinef) that are most important to monitor?

A

Wt. gain, HTN, electrolyte imblance

42
Q

What are some adverse effects of Glucocorticoid (Prednisone)?

A

Mild edema, take as prescribed, don’t stop abruptly and can lead to Cushing’s

43
Q

What is Addisonian Crisis?

A

Severe adrenal insufficiency (may be sudden or progress over several days)

44
Q

S/S of Addisonian Crisis?

A

Severe hypotension, circulatory collapse, shock, coma

45
Q

What are the 5 S’s to treat Addisonian Crisis?

A
Salt replacement (.9NS)
Sugar replacement (D5 electrolyte replacement)
Steroid Replacement (IV)
Support of physiological functioning (GI/resp/metabolism)
Search for and treat an underlying cause (ex. infection)
46
Q

What are important nursing interventions for fluid volume deficit in Addisons’s disease?

A

Physical s/s (dry furrows on tongue), VS, monitor labs/wt, increase fluid intake, and sit/stand slowly

47
Q

What are important nursing interventions for risk for injury in Addison’s disease?

A

Assess mental status, assess for hypoglycemia, assess VS (hypotension/tachycardia) and assess for dehydration