adrenal Flashcards

1
Q

adrenals anatomy + hormone

A

cortex:
glomerulosa - mineralocorticoid
fasciculata - glucocorticoid
reticularis - androgens

medulla: catecholamines

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2
Q

dexamethasone CRH test

A

dexamethasone 0.5 mg every 6 hours over 2 days for a total of 8 doses, administering CRH (1 μg/kg, intravenously) 2 hours after the last dose of dexamethasone, and measuring the serum cortisol 15 minutes later

pseudo-Cushing: <1.4 mcg/dl

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3
Q

Ddx

A

CAH
Adrenal neoplasms
Cushing Syndrome

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4
Q

1st step in evaluation

A

determine if with hx of glucocorticoid use

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4
Q

awake midnight cortisol test N value

A

<7.5 mcg/dl

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5
Q

asleep midnight cortisol test N value

A

<1.8 mcg/dl

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6
Q

1st step to determine source of cortisol

A

serum ACTH

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7
Q

determine if ectopic or pituitary ACTH

A

CRH test
high dose dexa test
petrosal venous catheterization

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8
Q
A
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9
Q
A
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10
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