Adipose Tissue Flashcards

1
Q

What chemicals does adipose release?

A
Leptin
CRP
TNF alpha
IL-6
Oestrogen 
Cortisol
Free fatty acids
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2
Q

What is the function of leptin in the body?

A

Tracks and monitors bodies adipose levels

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3
Q

If there are low levels of leptin what does this trigger?

A

Increased appetite

Decreased thermogenesis

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4
Q

If there are high levels of leptin what does this trigger?

A

Decreased appetite

Increased thermogenesis

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5
Q

What is the only drug licensed for weight loss?

A

Orlistat

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6
Q

What is the mode of action of orlistat?

A

Lipase inhibitor

Blocks dietary absorption of fat

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7
Q

What are some side affects of Orlistat?

A

GI diarrhoea

Steatorrhea

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8
Q

What are the three forms of bariatric surgery

A

Adjustable gastric band
Roux-en-Y gastric bypass
Vertical sleeve gastrectomy

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9
Q

What are the pros and cons of a gastric band?

A

Least invasive

However if there is dramatic weight loss the band can slip superiorly and inhibit any food intake

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10
Q

At what weight can you be considered for bariatric surgery?

A

BMI 40

BMI 35 with significant related health issues e.g. diabetes

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