ADHD Flashcards

1
Q

Define Attention deficit hyperactivity disorder

A
  • persistent pattern of inattention and/or hyperactivity-impulsivity that is more frequently displayed and more severe than is typically observed in individuals at a comparable level of development
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2
Q

Attention deficit hyperactivity disorder is characterized by what 4 criteria? For how long?

A
  1. inattention and/or hyperactivity-impulsivity
    • 6 or more symptoms for at least 6 months
  2. symptoms present prior to age 12
  3. symptoms present in 2 or more settings
  4. clear evidence symptoms interfere with, or reduce quality of social, academic or occupational functioning
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3
Q

what is the most common age of diagnosis for Attention deficit hyperactivity disorder

A
  • elementary school aged children
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4
Q

List the conditions that can co-occur in ADHD

A
  • learning disorder
  • oppositional defiance disorder
  • conduct disorder
  • substance abuse
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5
Q

List the pediatric scales that are used to rate Attention deficit hyperactivity disorder

A
  • Vanderbilt Assessment scales: > 4 yo
  • Conners comprehensive behavior rating scales: okay for preschool age
  • ADHD rating scale IV: okay for preschool age
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6
Q

List the adult scales that are used to rate Attention deficit hyperactivity disorder

A
  • ADHD self report scale (ASRS)
  • Conners adult ADHD rating scale (CAARS)
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7
Q

Attention deficit hyperactivity disorder can be caused by a decrease in availability of what neurotransmitters in the cortex

A
  • norepinephrine
  • dopamine
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8
Q

treatment of Attention deficit hyperactivity disorder in preschool children (aged 4-5 yo)

A
  1. behavior therapy is intial therapy
  2. medication only if needed
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9
Q

treatment of Attention deficit hyperactivity disorder in children > or = 6 yo

A
  1. medication
  2. behavioral interventions added
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10
Q

treatment of Attention deficit hyperactivity disorder in adults

A
  1. medication > psychotherapy
  2. atomoxetine if substance abuse is a concern
  3. antidepressants
  4. cognitive behavior therapy
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11
Q

List the three stimulants that are used in Attention deficit hyperactivity disorder to increase release of dopamine and norepinephrine

A
  • methylphenidate
  • dextroamphetamine
  • mixed amphetamine salts
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12
Q

stimulates come in what two formulations

A
  • short and long acting
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13
Q

list side effects of stimulants

A
  • appetite disturbance, weight loss
  • social withdrawal
  • irritability
  • nervousness
  • sleep disturbance
  • headache, abd pain
  • tics
  • contact dermatitis
  • Increased HR and BP
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14
Q

MOA of Atomoxetine

A
  • selective norepinephrine reuptake inhibitor
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15
Q

When is Atomoxetine used

A
  • used in tx of ADHD for people with h/o substance abuse
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16
Q

side effects of Atomoxetine

A
  • decreased appetite, weight loss
  • abd pain, N/V, dyspepsis
  • sleep disturbances
  • tics
  • severe liver injury
  • increase in suicidal thinking
  • cardiac risk
17
Q

what are the first line managment for ADHD

A
  • stimulants
18
Q

List Functions of Norepinephrine

A
  • mood, learning, memory
  • arousal, attention
  • appetite
19
Q

mania is associated with what level of NE release

A

increased NE release

20
Q

Bipolar disorder is associated with what level of NE release

A
  • increase and decrease in NE release
21
Q

caffeine increases release of what neurotransmitter which increases arousal/attention

A

NE

22
Q

appetite suppression causes increased release of what neurotransmitter in the hypothalamus

A
  • increase in NE
23
Q

Increased level of what neurotransmitter is associated with psychosis

A

DA

24
Q

What syndromes are associated with disorders of Dopamine

A
  • parkinsonism
  • Parkinson’s disease
  • Tourettes syndrome
25
Q

Common pathway for substance based and behavioral addictions is associated with what neurotransmitter

A
  • dopamine
    • DA system is basis for new anti-craving medications
26
Q

List the functions of Dopamine

A
  • smooth movement
  • subjective experience of pleasure/reward