Adenoviridae

Question 1

Family: adenoviridae

Answer 1

Non-enveloped, precisely hexagonal in outline
12 vertex penton capsomeres each with a fiber protrude from the surface of capsid
Intranuclear inclusion bodies are formed, containing large numbers of visions, often in para-crystalline arrays

Question 2

Family: adenoviridae- general properties

Answer 2

Many adenoviruses agglutinate RBCs
Hemagglutination occurring when the tips of penton fibers bind to surface receptors on RBCs
Some viruses are oncogenic in lab animals
Adenoviruses are relatively stable in the environment, but are inactivated easily be common disinfectants
Most of the adenoviruses have narrow host ranges

Question 3

Family: adenoviridae- pathogenesis

Answer 3

Many adenoviruses cause acute respiratory or gastroenteritis disease of varying severity 
-mostly subclinical infections
Immunosuppression 
Long periods of latency
Oncogenesis

Question 4

Family: adenoviridae- path- long periods of latency

Answer 4

Virus persists in lymphoid and other tissues, such as tonsils, adenoids, and Peyer’s patches
Reactivated in immunocompromised animals
Can be highly pathogenic in immunodeficient animals

Question 5

Family: adenoviridae- path- oncogenesis

Answer 5

Under specialized conditions, some adenoviruses have been shown to be oncogenic

Question 6

Genus Mastadenovirus

Answer 6

Mammalian adenoviruses

A single penton fiber projects from each vertex

Question 7

Genus Aviadenovirus

Answer 7

Avian adenovirus
Each penton fiber is bifurcated
Appear as two fibers extending from each penton base