Addition Reactions

Question 2

How do I add a Br to an alkene?

• Carbocation rearrangements possible
• Br in most substituted position

Answer 2

Use H-Br!

Question 3

How do I add an H and OH to an alkene?

Answer 3

• Use H₃O⁺ to get Markov. product.
• Use Hg(OAc)2 in water and THF THEN NaBH4 in water to get Markov. product with NO rearrangements.
• Use BH3 in THF THEN H2O2 in NaOH to get the anti-Markov. product with NO rearrangements.

Question 4

What are the conditions of oxymercuration/demurcuration

Answer 4

1. Hg(OAc)2 in water and THF
2. NaBH4 in water
3. Markov. product
4. NO rearrangements.