Addiction Medicine Flashcards
1
Q
Opiod use disorder
A
More effective to treat with medication
2
Q
Methadone
A
Full agonist
maintains tolerance, reduces effects of their use
3
Q
Buprenorphine
A
agonist
Sublingual - with or without naloxone (which is not absorbed sublingually) (suboxone, Zubzolve)
- Severe liver impairment - liver will not break down Naloxone)
Can induce withdrawals due to partial agonist effect
Heroin withdrawal 6-12 hours, methadone longer
Higher affinity than all opioids except fentanyl
Buprenorphine is not detected by drug screen
Implant - 6mo
Injections - 1month / 1 week (sublocade, CAM2038)
MAT clinic = Medically assisted treatment
4
Q
Opioid withdrawal symptoms
A
Drug craving Anxiety/ Restlessness GI upset Diaphoresis Tachycardia
5
Q
Suboxone
A
Buprenorphine / Naloxone combo
6
Q
Naltrexone
A
(lexicomp)
Pure opiod antagoinst / aslo used for alcohol withdrawl
Used first in MAT for MODERATE OUD
