Addiction Medicine Flashcards

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1
Q

Withdrawal symptoms in the absence of a drug

A

Physical dependence

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2
Q

A neurobiologic disease with genetic and psychosocial contributions leading to compulsive use and cravings despite harmful consequences

A

Addiction

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3
Q

4 common themes in clinical practice that can lead to addiction

A
  1. Early exposure, depression, difficulty coping with loss
  2. Unsafe recovery environment
  3. Family history, childhood abuse, and neglect
  4. Inappropriate gateway prescription use, co-morbid mental illness
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4
Q

3rd leading preventable cause of death in the US

A

Alcohol

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5
Q

More than half of alcohol related deaths are linked to ___ ___

A

Binge drinking

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6
Q

Drinking 8 or more drinks 4 or more times/month

A

Binge drinking

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7
Q

Do all binge drinkers show all behaviors characteristic of a substance abuse disorder?

A

NO

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8
Q

What is the most critical time period in a patient receiving outpatient treatment for addiction?

A

The first few weeks

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9
Q

Relapse prevention is a form of?

A

CBT

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10
Q

Identifies cognitive, behavioral, and environmental risk factors for relapse, as well as rehearsing coping responses for those risk factors

A

Cognitive behavioral therapy

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11
Q

What is generally efficacious in reducing substance use and improving psychosocial outcomes when compared to other active treatments, no treatment, or other control conditions?

A

Relapse prevention

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12
Q

What is one factor that is commonly associated with relapse? (There are many but this one was bolded and italicized, so it must be important)

A

Low motivation for recovery

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13
Q

What are the two NTs associated with ETOH withdrawal?

A

GABA and Glutamate

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14
Q

GABA is a _____ NT

A

inhibitory

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15
Q

Glutamate is an ___ NT

A

excitatory

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16
Q

How do alcoholics function at an alcohol level that would normally induce sedation or coma?

A

EtOH binds to GABA receptors and supplements ordinary inhibitory signals

17
Q

Sudden EtOH cessation leads to DECREASED ???

A

INHIBITORY tone

18
Q

EtOH interferes with glutamate-triggered ____ receptor activation

A

NMDA

19
Q

What happens to glutamate with sustained and increasing alcohol use?

A

Accommodation occurs and more glutamate receptors are produced

20
Q

Sudden etOH cessation leds to INCREASED ???

A

EXCITATORY tone that is unopposed by the concurrent lack of inhibitory tone

21
Q

What is the warning sign of minor withdrawal symptoms in patients who suffer from EtOH abuse?

A

BP, HR, and temp aberrations 6-36 hours after last drink

22
Q

Alcohol withdrawal is a ___ diagnosis

A

Clinical

23
Q

Peak symptoms of heroin withdrawal occur after?

A

3-4 days

24
Q

How do you treat EtOH withdrawal?

A

IV fluids, vitamins/electrolytes, PRN medications, seizure/DT prophylaxis drugs (benzos, phenobarb, tegretol)

25
Q

What is very prevalent among opiate users?

A

Hepatits C

26
Q

Withdrawal characterized by: Increased anxiety, palpitations, tachycardia, restlessness, peripheral sensory disturbances

A

Benzodiazepine

27
Q

Stopping benzodiazepines at high doses carries a risk for ?

A

Seizure

28
Q

Benzodiazepines increase which neurotransmitter?

A

GABA

29
Q

What can you use for a benzo detox?

A

Phenobarbital

30
Q

Should you ever ask a patient struggling with substance abuse if they want to quit smoking at the same time as they are recovering from another drug?

A

NO leave them alone and let them have their sin sticks