Addiction Med-Zalon Flashcards
(blank) babies are born yearly after in-utero substance exposure
300,000
Approximately (blank) children are in foster care
About (blank) of these placements are due to substance abuse
500,000
¾
What are the co-morbidites with substance abuse?
Depression
Anxiety (esp. PTSD)
Personality disorder (esp. borderline personality disorder – BPD)
Bipolar disorder
SUbstance abuse is often a form of (Blank) and (Blank) behavior
escape and avoidance behavior
25-60% of clients with (bank) also have SUD
BPD
Severity and treatment outcomes of SUD are worse in (blank) conditions
co-occuring
THe lifetime prevalence of BPD in general US populations is (blank), where in netherlands it is (blank)
Why?
6%
1%
THey spend more on healthcare so people are able to get more help
What is the lifetime prevalence rate of alcohol use disorder?
30%
Point prevalence of “high risk” drinking is about (Blank)%.
Prevalence is higher in what group?
30%
younger age groups
What are medical complications associated with Alcohol?
- Neurological – dementia, psychosis, seizure, depression
- Liver, CV, pancreas
- suicide
- MVAs and other traumas
(blank) use correlates to violence (both perpetrator and victim), more so than other drugs
alcohol
Patients that substance abuse disorders have increased (blank) and (Blank) from all medical conditions. Why?
morbidity and mortality
-they are harder to provide care for because of their medical complication and relationship problems (medicine is dependent upon good social support)
What is the number one prescribed drug in the US?
What is the number 2 drug?
Vicodin
131. 2 million prescriptions in 2010, 99% of worlds supply
- simvastatin (94 million)
The annual prevalence of nonmedical non-heroin narcotic use among 12th graders increased from 3.5% in 1991 to (blank)% in 2007
9.2%
What age group uses nonmedical prescription opiods the most….college, 12th grade, or young adults?
12th grade
Over the years, ED visits from narcotic use as (decreased/increased)
What types of narcotic analgesics have caused the most ED visits?
increased
-hydrocodone (and hydrocodone combo), oxycodone (and oxycodone combos)
Recently, teens perceive prescription drugs as easier to (blank) than beer
buy
What is diversion?
use a prescription for something else rather than intended purpose (i.e takin someones vicodin for fun)
What are some iatrogenic causes of SUD (physician caused)?
- misunderstanding nature of addiction,
- notion that addiction is characterized by physical dependence or tolerance
- “addiction is vague term”
- DSM5 only describes SUD and grades the severity on a spectrum
T or F
Enough painkillers were prescribed in 2010 to medicate every American adult round the clock for a month
T
(blank) often correlates to physical signs of dependence and tolerance. However can also be suspected based on behavioral signs of (blank)
Addiction
compulsive use
What are signs of compulsive use?
use despite harmful consequences, use that is escalating, pervasive urges to use, high risk behaviors, failed attempts to stop or reduce use.
What did the DSM5 eliminate about the description of SUD? What did they combine?
the difference b/w abuse and dependence
-combined those features into a single spectrum oriented disorder with severity grading
What is the DSM5 criteria for SUD?
Taken in larger amounts than intended. Failed attempts to control or stop. Excessive time given to use or recovery. Strong urges to use. Functional impairment. Ignoring harmful consequences. High risk behaviors. Withdrawal or efforts to avoid withdrawal. Tolerance: escalating use/ diminishing effects
SInce the DSM5 combined the criteria for substance abuse and substance dependence, they made a severity spectrum to show difference between dependency,,,, what is considered mild, moderate and severe?
Mild: 2-3 symptoms
Moderate: 4-5 symptoms
Severe: 6 or more symptoms
How do you screen for SUD?
CAGE questions (developed for alcohol, has also been used for other substances)
- Cut down?
- Annoyed?
- Guilty?
- Eye-opener? (i.e having withdrawal symptoms and need substance to counteract symptoms)
What is this:
the proportion of cases that return true positives
What is this:
the proportion of non-cases that return true negatives
sensitivity
specificity
***ideally you want max sensitivity and max specificity
If you make diagnostic criteria less stringent, you catch more in your net but will runs the risk of (misdiagnosis resulting in (blank). What would you summarize this as?
false positives
In crease in sensitivity but decrease in specificity
If you make diagnostic criteria more stringent, you will “let some get away” but those you “catch” will me more likely to be correctly diagnosd. This is a decrease in (blank) with an increase in (blank)
sensitivity
specificity
(blank) tests usualy designed for high sensitivity
screening
(blank) tests usually designed for high specificity
confirmatory
What is a PPV?
What is NPV?
- proportion of test positives that are true positives.
- proportion of test negatives that are true negatives.
The higher your cage score the higher the (blank)
PPV
CAGE score of 1=0.54, 2=0.75, 3=0.87, 4=0.92
T or F
SUD is a highly heritable phenotype
How so?
T
1st degree relatives of those with SUD may have as much as 8x risk.
SUD is a behavioral illness that has a phenotype that correlates to both (Blank and blank) variables
heritiable and acquired variables