Addendum of 2 slides to Diabetes-1 (1)

Question 1

What are the two distinct phases of insulin release observed in healthy subjects?

Answer 1

Acute phase (first-phase response) and second phase response

The acute phase occurs within the first hour, followed by a gradual decrease returning to fasting levels by 3 hours.

Question 2

How do insulin levels behave in diabetic subjects compared to healthy subjects?

Answer 2

In diabetic subjects, insulin levels remain high and do not return to fasting levels

This contrasts with healthy subjects where insulin levels decrease after the acute phase.

Question 3

What happens to high glucose levels in healthy subjects after an oral glucose tolerance test?

Answer 3

High glucose levels quickly return to low fasting levels

This indicates effective insulin response in healthy individuals.

Question 4

What is the condition characterized by persistently high glucose levels in diabetic subjects?

Answer 4

Hyperglycemia

Hyperglycemia occurs when high glucose levels persist for a long time in diabetic individuals.

Question 5

True or False: In diabetic subjects, the phases of insulin release are distinguishable.

Answer 5

False

Diabetic subjects do not show distinguishable phases of insulin release.

Question 6

Fill in the blank: In healthy subjects, insulin levels return to fasting levels by _______.

Answer 6

3 hours

This return occurs after the second phase of insulin release.