adaptations for nutrition Flashcards
describe the structure of the mammalian gut wall
- along its length, the gut wall consists of 4 tissue layers surrounding the lumen of the gut.
- the proportions of the different layers of the gut wall vary, depending on the function of the part of the gut
what are the 4 tissue layers that surround the lumen of the gut?
- serosa
- muscularis
- submucosa
- mucosa
what can you say about the thickness of these layers?
the thickness of these layers varies in different regions of the digestive system
e.g stomach, ileum
describe the serosa
- this is the outermost layer
- contains connective tissue which protects the gut wall
- helps to reduce friction with other abdominal organs during peristalsis
describe muscularis
- composed of 2 layers : the inner circular muscles and the outer longitudinal muscles
- they make coordinated waves of contraction (peristalsis), pushing the ball (bolus) of food along the alimentary canal
describe submucosa
- consists of connective tissue containing blood and lymph vessels which remove the absorbed products of digestion
- this layer also contains the nerves which coordinate peristalsis
describe mucosa
- lines the gut wall and is the inner most layer
- the epithelium secretes mucus which lubricates and protects the mucosa
- in some regions of the gut, it secretes digestive juices and in others, it absorbs digested food
what is the function of the mouth?
ingestion
- mechanical digestion of food due to crushing action of the teeth
- chemical digestion of starch by salivary amylase
what is the function of oesophagus?
carriage of food to the stomach by peristalsis
what is the function of the stomach?
- mechanical digestion by contraction of stomach muscles to churn the food
- secretion of hydrochloric acid
- chemical digestion of proteins by enzymes
what is the function of the duodenum?
receives pancreatic juice from the pancreas and bile from the gall bladder
- chemical digestion of carbohydrates, fats and proteins by enzymes
what is the function of the ileum?
- chemical digestion of carbohydrates, fats and proteins by enzymes
- absorption of digestion food
what is the function of the colon?
absorption of water
what is the function of the rectum?
storage of faeces
what is the function of the anus?
site of egestion
define ingestion
taking food into the body through the mouth
define digestion
the breakdown of large insoluble molecules into soluble molecules that are then small enough to be absorbed into the blood.
how many types of digestion are there?
describe them.
MECHANICAL DIGESTION - cutting and crushing by teeth and muscle contractions of the gut wall, increases the surface area over which enzymes can act
CHEMICAL DIGESTION - breakdown using digestive enzymes, bile and stomach acid also contribute to this
define absorption
the passage of small soluble molecules and ions through the gut wall into the blood
define egestion
the elimination of indigestible waste
e.g cellulose (dietary fibre)
what 4 main functions does the human gut perform?
- ingestion
- digestion
- absorption
- egestion
why must food be digested?
- food molecules are insoluble and are too large to cross membranes and be absorbed into the bloodstream
- polymers must be converted to their monomers, so they can be assimilated into molecules needed by body cells
define peristalsis
wave of muscular contractions and relaxations of the gut wall which propel the contents along the whole length of the gut
what aids peristalsis in the intestines?
dietary fibre
describe the steps in peristalsis
- contraction of circular muscles behind food
- contraction of longitudinal muscles ahead of food
- contraction in circular muscle layer forces food forward
describe the gut
- long, hollow, muscular tube
- allows movement of its content in one direction only
what does saliva contain?
- amylase
starch –> maltose - bicarbonate ions
these create an optimum pH for amylase - mucus
this lubricates the food
food is mechanically digested in the mouth, explain how
food is mixed with saliva by the tongue and chewed with the teeth
this increases the surface area of food for the enzymes to work on
what are the 2 regions of the small intestine?
ileum and duodenum
what is the function of the sphincter muscles at the base of the stomach?
releases partially digested food into the duodenum
what is the role of bile in the small intestine?
to emulsify lipids
where is bile produced and stored?
- produced in the liver
- stored in the gall bladder
what are endopeptidases?
they hydrolyse peptide bonds within the protein molecule
e.g pepsin and trypsin
what are exopeptidases?
they hydrolyse peptide bonds at the end of shorter polypeptide chains to make amino acids, dipeptides
what does the gastric juice contain?
- mucus
- hydrochloric acid
- pepsin
describe the mucus in the gastric juice
- secreted by goblet cells which line the mucosa
- forms a protective lining which protects the stomach wall from digestive enzymes and hydrochloric acid
- helps to lubricate the food
describe the hydrochloric acid in the gastric juice
it lowers the pH of the stomach contents to pH2 to create an optimum environment for enzymes and kills bacteria
describe pepsin in the gastric juice
- secreted as inactive pepsinogen
- this is a peptidase that works optimally in the acidic environment of the stomach
- activation of pepsinogen by hydrochloric acid forms active pepsin
why are enzymes secreted in an inactive form?
as the active form would digest cells of the stomach (autolysis)
what is the function of the duodenum?
digestion of carbohydrates, fats and proteins
describe the duodenum
it is the first section of the small intestine
- recieves secretions from the liver and pancreas
- the food coming from the stomach is lubricated by mucus and the hydrochloric acid is neutralised by alkaline secretion (NAHCO3) from cells in the submucosa
BILE
what is bile?
what does bile contain?
what is the function of bile?
BILE
- made in the liver
- stored in the gall bladder
- passed through the bile duct into the duodenum
- contains bile salts which are hydrophilic and hydrophobic
- they emulsify lipids present in the partially digested food and breaking up large globules into smaller droplets, increasing surface area for lipase action
- bile is alkaline, and so neutralises the acid in the food coming from the stomach creating an optimum pH environment for the enzymes in the small intestine
what is pancreatic juice?
- secreted by specialised cells in the pancreas
- it enters the duodenum through the pancreatic duct
what are the duodenal secretions?
what are their functions?
sodium hydrogen carbonate:
raises the pH to make pancreatic juice more alkaline
enterokinase:
an enzyme that converts trypsinogen to trypsin
what are the pancreatic secretions?
what are their functions?
endopeptidases:
hydrolyses protein to shorter polypeptides
trypsinogen:
inactive enzyme converted into the endopeptidase trypsin by enterokinase
pancreatic amylase:
chemically digests any remaining starch to maltose
lipase:
hydrolyses lipids into fatty acids and glycerol
what is the function of the ileum?
absorption
how is the ileum adapted for absorption?
- it is very long
- its lining is folded
- on the surface of the folds are villi
- the epithelial cells lining the villi has microscopic projections called microvilli
these helps to INCREASE SURFACE AREA
what are the 2 specialised cells in the mucosa of the ileum?
- columnar epithelial cells
- goblet cells
what are the 2 main adaptations of the columnar epithelial cells?
- microvilli providing a large surface area for absorption of the products of digestion
- large numbers of mitochondria to produce ATP energy for active transport
what is the function of the goblet cell?
secretes mucus
- lubricates and protects the lining of the intestine
describe the structure of a villus
- columnar epithelial cells
- goblet cell
- lacteal
- blood capillary
- crypt of luberhuk
what is the lacteal?
lymphatic capillary which absorbs dietary fats
glycerol & fatty acids