Acutely Unwell Adult Flashcards

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1
Q

What is shock?

A

State of hypo-perfusion
Tissues do not receive adequate blood supply
Cellular and tissue hypoxia

‘Life threatening, generalised form of acute circulatory failure with inadequate oxygen delivery’

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2
Q

What force is relevant in blood vessels?

A

Capillary hydrostatic pressure

Changes throughout the capillary from venous to arterial end

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3
Q

What movement happens at the arterial end?

A

Fluid exits capillary since hydrostatic pressure > blood coloidal osmotic pressure

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4
Q

What movement happens at the venous end?

A

Fluid re-enters capillary since hydrostatic pressue < blood coloidal osmotic pressure

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5
Q

In shock where is the fluid lost to?

A

Interstitium

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6
Q

Explain distributive shock

A
Inflammation
Increased vascular permeability 'leakier' 
Colloid osmotic pressure decreases
Decreased venous reabsorption
Fluid loss to the interstitum
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7
Q

Explain hypovolaemic shock

A

Loss of circulating blood volume

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8
Q

Explain cardiogenic shock

A

Failure of the pump

Problem with output - ‘delivery of blood’

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9
Q

Explain obstructive shock

A

Problem with output - ‘delivery of blood’

Obstruction within the circulatory system

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10
Q

Describe the pathophysiology of burns

A

Burn
Tissue damange
Clot formation and firbin
Necrotic cells release permeability factors
White cells can invade space
White cells in turn release permeability factors
White cells release cytokines
Eventual recruitment of fibroblasts promoting angiogenesis

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11
Q

Why do burns cause distributive shock?

A

Large number of permeability factors that are released at the site of damage

But these factors end up in the blood stream

Becomes a systemic problem as these factors invade healthy tissue

Overall blood vessels become leakier and more fluid is lost to the interstitum

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12
Q

Why is it called distributive shock?

A

Redistribution of fluid from in vessels to interstitum

‘Fluid moved to other spaces’

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13
Q

Why does blood become more viscous in shock?

A

Fluid loss but blood cells remain

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14
Q

Why do burns cause hypovolaemic shock?

A

Normally skin acts as protective barrier to water loss

Dermis becomes exposed and more evaporation occurs

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15
Q

Why do burns cause cardiogenic shock?

A

Cardiac stress
Heart responds to the volume of blood in it
Release of cytokines also contribute to cardiac stress

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16
Q

Which type of shock contributes the most in burns?

A

Distributive is by far the largest

Other two components are important

17
Q

What in a patient’s history indicates need for fluid resus?

A
Previous limited intake
Thirst
Abnormal losses (trauma/bleeding)
Comorbidities
Vomiting and Diarrhoea
18
Q

What in the clinical examination indicates need for fluid resus?

A
Tachycardia (>90)
Low BP (<100mmHg)
Capillary refill (>2s)
JVP
Postural hypotension
Poor skin turgor
Dry mucous membranes
19
Q

What can cause a volume shift?

A

Sepsis
Anaphylaxis
Neurogenic shock

20
Q

What metrics on monitoring can indicate fluid resuss?

A

NEWS
Fluid balance charts
Weight

21
Q

What formula is used to calculate how much fluid is given to burn patients?

A

Parkland formula
4ml x TBSA (%) x body weight (kg)
Over 24 hours

22
Q

How do you calculate TBSA burn?

A

Wallace’s rule of 9s
18% front chest
9% for each arm

23
Q

How do you determine when you give the fluid?

A

50% in the first 8 hours

50% in the next 16 hours

24
Q

What are three commonly used fluids?

A

5% dextrose
Ringers Lactate (Hartmann’s)
0.9% Saline

25
Q

Which fluid is most commonly used?

A

Saline
Cheaper
In practise Ringer’s is not a whole load better

26
Q

Why would colloid solution in theory be great for shock?

A

Increase plasma protein in the capillary
Which would draw fluid back in
Does not work in practice
Associated with allergic responses

27
Q

What is the skin layer affected in an epidermal burn?

A

Epidermis

28
Q

What is the skin layer affected in an superficial partial thickness burn?

A

Upper dermis

29
Q

What is the skin layer affected in an deep partial thickness burn?

A

Extends into the deep dermis
Affecting the vascular plexus
Not all of the dermis is affected

30
Q

What is the skin layer affected in a full thickness burn?

A

has extended through the entire
thickness of the dermis and
no dermal tissue remains
(Third degree)

31
Q

What are some psychological impacts of burns?

A
Flashbacks
Dissociation
Avoidance
Insomnia
Hyperarousal
Hypoarousal
32
Q

How can these problems be dealt with?

A

CBT
Anti-depressants
Sleeping pills/Other methods