Acute Stroke Flashcards
Lists modifiable risk factors for strokes
Hypertension Smoking Alcohol Diabetes High cholesterol Obesity Diet
List non-modifiable risk factor for stroke
Age
Race
Gender
Family history
Is smoking a modifiable or non-modifiable risk factor for stroke?
modifiable
Which arteries supply the frontal lobe?
Anterior cerebral artery
Middle cerebral artery
Which arteries supply the parietal lobe?
Anterior cerebral artery
Middle cerebral artery
Damage to the Anterior cerebral artery is likely to cause injury in which part of the brain?
Frontal Lobe
Parietal lobe
Which arteries supply the occipital lobe?
Posterior cerebral artery
Which arteries supply the brainstem?
Vertebral basillar
Which arteries supply the cerebellum?
Basilar
Posterior inferior cerebellar artery
Anterior Inferior Cerebellar Artery
Superior Cerebellar Artery
Which arteries supply the Hippocampus?
Posterior Cerebral Artery
Which arteries supply the Temporal lobe?
Middle cerebral artery
Posterior cerebral artery
Damage to the middle cerebral artery could cause injury in which part of the brain?
Frontal lobe
Damage to the posterior cerebral artery could cause injury in which part of the brain?
Frontal lobe
parietal Lobe
Damage to the posterior inferior cerebellar artery could cause injury in which part of the brain?
Occipital lobe
hippocampus
temporal lobe
Damage to the Anterior inferior cerebellar artery could cause injury in which part of the brain?
cerrebellum
Damage to the superior cerebellar artery could cause injury in which part of the brain?
cerebellum
Damage to the vertebral basilar artery could cause injury in which part of the brain?
brainstem
What is the brainstem made up of? (3)
midbrain
pons
medulla
What is most common type of stroke in the UK?
ischemic stroke
What are the common causes of ischaemic stroke?
large vessel disease (i.e. carotid stenosis)
Atrial Fibrillation
Whyat are common causes of haemorrhagic strokes?
hypertension
aneurysms and avms
How does ischaemic stroke present on a ct scan?
oxygen deprived areas look slightly darker
How do haemorrhagic strokes present on a ct scan?
concentrated light/white areas
A head CT scan shows areas of slightly darker brain tissue.
what type of stroke is the patient likely to have?
ischaemic stroke
A head CT scan shows an concentrated white mass in the brain
what type of stroke is the patient likely to have?
haemorrhagic
What is the aim of acute reperfusion therapies?
ton rstore blood flow either through or around blocked arteries prior to a stroke occuring.
What is is thrombolysis (ART)?
The administration of drug treatment to lyse the clot in occluded vessel
What drug is usually administered to lyse a clot?
alteplase
How long from the onset of a stroke can thrombolysis be used?
4.5 hours
what is a Thrombectomy?
An interventional procedure to remove the clot from an occluded vessel.
How long from the onset of a stroke can thrombectomy be done?
6 hours
What are some of the contraindications for thrombolysis?
Haemorrhage on CT
Extensive established
ischaemia on CT
On anticoaugulation
Recent major surgery
Bleeding abnormality
how should thrombolysis be administered?
dose: 0.9mg/kg
provide 10% of total dose as bolus then 90% via infusion over 1 hour
What device is used for a thrombectomy?
a stent retriever device
what are some of the indications for a thrombectomy?
Stroke onset within 6 hours
Ongoing neurological
deficit
All ages
Eligible or ineligible for
thrombolysis
Large vessel occlusion on
CT angiogram
what are some of the contraindications for a thrombectomy?
Haemorrhage on CT
Extensive established
ischaemia on CT
Resolving neurological
deficits
What steps are taken for the management of an acute hemorrhage?
Reversal of anticoagulation:
- Vit K and prothrombin complex for warfarin
- Iduracuzimab for dabigatran
- Prothrombin complex for other direct oral
anticoagulants
Immediate blood pressure control
- Aim for <140mmHg within 24 hours and for 7 days