Acute Myeloid Leukaemia and Myelodysplatic Syndromes Flashcards
1
Q
What are the clinical features of AML?
A
rapid tempo onset features of bone marrow failure
2
Q
What is the usual induction chemotherapy regimen for AML?
A
cytarabine for 7 days followed by an anthracycline for 3 days
3
Q
Why should patients have a TTE prior to chemotherapy for AML?
A
anthracyclines can cause cardiomyopathy
4
Q
What additional treatment should be given to patients with a FLT3 mutation?
A
midostaurin
5
Q
What is the treatment for high risk MDS patients?
A
azacitidine therapy
consider allogenic BM transplant in younger patients
6
Q
What is the treatment for 5q minus syndrome?
A
lenalidomide
