Acute Leukemias II

Question 1

B-ALL with t(9;22)(q34;q11.2); BCR-ABL1: age group and prognosis

Answer 1

• adult

- the worst

Question 2

B-ALL with translocations of 11q23; MLL: age group and prognosis

Answer 2

• neonates and young infants

- poor

Question 3

B-ALL with t(12;21)(p13;q22); ETV6-RUNX1: age group and prognosis

Answer 3

• childhood

- very favorable

Question 4

AML with t(8;21)(q22;q22); RUNX1-RUNX1T1: age group and prognosis

Answer 4

• young

- relatively good

Question 5

AML with inv(16)(p13.1;q22) or t(16;16)(p13.1;q22); CBFB-MYH11: prognosis

Answer 5

• young

- relatively good

Question 6

Acute promyelocytic leukemia with t(15;17)(q22;q12); PML-RARA: age group and prognosis

Answer 6

-better remission rates with ATRA/arsenic therapy

Question 7

AML with t(1;22)(p13;q13); RBM15-MKL1: age group and prognosis

Answer 7

• infants with DS

- relatively good

Question 8

AML with abnormalities of 11q23; MLL: prognosis

Answer 8

-poor prognosis