Acute Intracranial Problems Notes Flashcards
3 essential volume components of the skull
Brain Tissue
Blood
Cerebrospinal Fluid (CSF)
Primary Injury
Occurs at the initial time of injury
Secondary Injury
Effects of the primary injury that can appear in a few hours to a few days.
Intracranial Pressure (ICP)
Pressure of CSF fluid within the brain.
Factors that influence ICP
Arterial Pressure Venous Pressure Intraabdominal Pressure Posture Temperature Blood Gases
Monro-Kellie Doctrine
The 3 components must stay in a constant volume overall.
Only affects when the skull is closed.
Brain compensates in any component if one component is displaced more than others.
Normal ICP ranges
5-15 mmHg
Cerebral Blood Flow (CBF)
Blood supply given to the brain in any given time period, usually 1 minute.
Cerebral Autoregulation
Automatic adjustment that the brain does to maintain a constant blood flow when arterial BP changes.
Normal MAP
60-100 mmHg
Most people have 70mmHg
Critical to maintain MAP when ICP is increased
Cerebral Perfusion Pressure (CPP)
Pressure needed to ensure blood flow to the brain.
Normal CPP
60-100 mmHg
How to calculate MAP
(SBP+2(DBP))/3
How to calculate CPP
CPP=MAP - ICP or
CPP= Flow x Resistance
Factors Affecting Cerebral Blood Flow
CO2
O2
Hydrogen ions (H+)
Why is it critical to maintain CBF?
To preserve tissue and minimize secondary injury.
Prevent brainstem compression and brain herniation.
3 Types of Cerebral Edema:
Vasogenic
Cytotoxic
Interstitial
Vasogenic Cerebral Edema
Most common type
Characterized by leakage of large molecules from capillaries into surrounding extracellular space.