Acute Interstitial Nephritis Flashcards

1
Q

Typical symptoms of acute interstitial nephritis

A

Fever, rash, eosinophilia

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2
Q

Most common cause of AIN?

A

Medications:

  • Penicillin
  • Rifampicin
  • NSAIDs
  • Allopurinol
  • Furosemide

Systemic disease; SLE, sarcoidosis and Sjogren’s syndrome
Infection: Hanta virus, staphylococci

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3
Q

Pathophysiology of AIN

A

Marked interstitial oedema and interstitial infiltrate in the connective tissue between renal tubules

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4
Q

Features

A

fever, rash, arthralgia
eosinophilia
mild renal impairment
hypertension

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5
Q

Investigations

A

Sterile pyuria

White cell casts

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