Acute Inflammation Flashcards
Acute inflammation is specific/non-specific reaction that deliver ___ to site of problem.
Non-specific, leukocytes
In acute inflammation, mediators can be generated from __ and __.
Cells, plasma protein
Cell types that produce mediators of acute inflammation are:
Platelets, neutrophils, monocytes/macrophages, mast cells
Acute inflammation mediators generated from plasma proteins are produced in the ___.
liver
__ is an inflammatory response of characterized by exudation of fluid and plasma proteins.
Edema
Inflammatory response results in emigration of __.
Neutrophil
In the inflammatory response, __ cells degranulate and release signals like __.
Mast, histamine
When released into vasculature, histamine acts on __ and __ to allow __ to leak from __.
Smooth muscle, endothelial cells, exudate, blood
Leukocyte migration through blood vessels:
Roll -> activated, adhere to endothelium -> transmigrate across endothelium -> migrate toward chemoattractants
In acute inflammatory resopnse, __ (celll) act for the first 6-24 hours followed by __ (cell) for the next 24-48 hours.
neutrophils, monocytes
Upon arrival at the site of infection, monocytes differentiate into __.
Macrophages
In Inflammatory response, two mechanisms of repair are:
1) Regeneration of cells
2) Scarring with fibrous tissues
usually combination of two
Only differentiated monocytes carry out phagocytosis. T/F
F: neutrophils also phagocytize
4 characteristics of histology of acute inflammatory response:
Neutrophils, macrophages (time), edema, bv dilation
Immature neutrophils are called __ or __.
Stab cells, band forms
