Acute Inflammation Flashcards
Cardinal Signs of Inflammation
Reddening, swelling, increased heat, pain, and loss of function
Opsonise
Coat
Fibrin
Creates clots, immobilizes irritant
Stages of acute inflammation
Vascular phase, Exudative phase, Migration of Acute Inflammation
Vascular phase
Initial phase and hyperemia
Hyperemia
Arteriole and capillary dilation
Inital phase
First step in the vascular phase of acute inflammation. Momentary arteriole constriction
Exudative Phase
Mast cells cause fluid to leave the circulation and enter tissues. Swelling
Migration of Acute Inflammation
WBC and leukocytes move to the periphery of the blood vessel
Degranulation
Escape through tight junctions and go to damaged site.
Eosinophils
Prominent in parasitic infections and local allergic reaction
Mast Cells
Their degranulation causes the release of histamine
Basophils
Rarely associated with disease in animals
What acts on temperature control centers in the hypothalamus
Pyrexia. Fever or Pyrogens
Functions of inflammatory effusion
Dilute, opsonise/coat, wash away toxic agent and spring antibodies to site
Classification of fluid by type/Effusion
Snakes Can Fit Down Hose Pipes
Snakes
SEROUS inflammation. Due to mild vascular injery
Can
Catarrhal Inflammation. Mild on mucous membranes
Fit
Fibrous Inflammation. Severe endothelial injury
Down
Diptheritic Inflammation. More severe form of fibrous. Considerable necrosis.
Hose
Hemorrhagic inflammation. Severe. Hemorrhage is the main component.
Pipes
Purulent inflammation and abscess formation. Pus is the main feature.
Deleterious effect of inflammation
Local tissue swelling
