Acute Glomerulonephrit Flashcards
What is the main symptom of glomerulinephritis?
Hematuria
How does the damage occur?
Immune complex or/and complement deposition in glomerules
Which types of antibodies deposit where?
Kations == subepithelial
Anions == subendtothelial
Notr == basal membrane
How many hematuria types are exist?
Microscobic == no color, RBC in urine
Macroscobic (gross) == color change
Red color == urine tract bleeding
Dark/brown color == glomeruler bleeding
How can dipstick test can be false positive?
It can be positive by hemoglobin or myoglobin without RBC in urine
Difference of nephrotic and nephritic syndromes?
Nephrotic syndrome == >3.5g/day proteinuria, podocyte damage
Nephritic syndrome == < 2.5g/day proteinuria, endothel damage, hematuria
What is the most common infectiosus nephrit reason?
Group A Streptococcus
What types of RBC’s can be seen in urine?
Monomorphic == Urinery tract
Dismorphic == Glomeruler
How do we classify bacteries of streptococcus?
M protein
What deposit in post-streptococcus Glomerulonephritis
IgG-C3-C1q
Main symptom of post-strep nephritis
Gross hematuria
What we can search after pharyngitis?
ASO
Treatment of post-strep nephritis?
Supportive
What is the most common glomerulophrit form?
IgA Nephropaty