Acute Care - Toxins + Ventilation Flashcards
what is an overdose of paracetamol classified as?
150mg/kg
so usually >12g/day
what are features of opiod overdose?
pinpoint pupils
low RR
decreased consciousness
what is an overdose of TCAs classified as?
10mg/kg
20-30mg/kg is lethal
features of TCA overdose?
warm skin brisk reflexes sedation urinary retention pupils poorly reactive and dilated (anticholinergic - sympathetic)
Ix for suspected overdose?
ABCDE FBC, U+Es, LFTs, coag BM ECG weight ABGs serum conc (known toxin)
Tx for TCA overdose?
IV sodium bicarbonate
Tx for opiod overodse?
naloxone
short half life so repeat dose every 30ish mins
Tx for paracetamol overdose?
IV N acetylcysteine (within 8hrs of dose)
after 4 hrs -> check paracetamol and salicylate levels
after 8hrs -> check again
what can be done if toxin ingested within 1hr?
charcoal decontamination
IV fluids
what is the Tx for benzos?
flumazenil
features of aspirin overdose?
tinnitus
vomiting
dehydrated
hyperventilation
Tx for Bb overdose?
glucagon
Tx for aspirin overdose?
supportive charcoal fluids <400 sodium bicarbonate >400 haemodialysis >700
features of salbutamol overdose?
agitated tremor tachy palps hypokalaemia
features of CO poisoning
headache malaise nausea vomiting erythema