Acute Bilateral Leg Weakness **** Flashcards
Spinal cord lesion - intrinsic causes
- Infection
- Inflammation
- Metabolic
- Others - 2
EBV, syphilis
Transverse myelitis, MS
B12 deficiency - myelin sheath is damaged
Primary tumour
Spinal stroke
Spinal cord lesion - extrinsic causes - think about what could compress the cord
Tumour - local or mets
Haematoma
Abscess
Trauma
Key levels and impairments:
Where is the phrenic nerve and what happens if there is a lesion at or above this?
Above what level are intercostal muscles affected?
C3-5
Impaired ventilation
Above T8
Spinal cord compression:
Causes - non-neoplastic
Causes - neoplastic
Trauma
Vertebral crush fracture due to osteoporosis
Slipped disc
Infection - epidural abscess, TB
Extradural mets from breasts, lungs etc.
CNS cancer
Spinal cord compression - Presentation
How does it start?
What makes the above worse?
Then Sensory loss - symmetry? where?
Then motor weakness - where?
What happens to the reflexes, tone, sphincter function?
In what patient should alarm bells start ringing if they have back pain or impaired mobility or sensation?
Back pain
Lying and coughing
Symmetrical sensory loss - 1-2 dermatomes below lesion
Legs
Hyperreflexia
Hypertonia (spastic paraparesis)
Sphincter dysfunction (hesitancy, frequency and later retention)
Cancer patients - mets
Spinal cord compression - Management
What med is given first? route? how long for?
Imaging - 2 types
Definitive Rx
Dexamethasone PO/IV loading dose then daily - reduces oedema therefore reduces pain
MRI whole spine
X-ray in trauma
Neurosurgery or radiotherapy
Chemo
Spinal stenosis:
What is it?
How is it different from other types?
An abnormal narrowing of the spinal canal or neural foramen that results in pressure on the spinal cord or nerve roots.
Affects both cords and roots
Spinal stenosis - Presentation
Main symptom
What about the legs? - 2
Where is the pain? - 2
When are symptoms worsened and relieved?
Neurogenic intermittent claudication
Leg weakness and numbness (motor and sensory)
Back and buttocks
Lumbar lordosis - standing up and arching back
Flexion
Spinal stenosis - Management:
What type of exercises can be done?
Meds - 1 orally and 1 epidurally?
Surgical intervention and in who? Risks of spinal surgery?
Bracing and strengthening exercises
NSAID’s
Corticosteroids
Decompression in this with debilitating pain
Nerve damage
Continued pain
Infection
CSF leak
Conus medullaris syndrome:
What presentation do you have - UMN/LMN?
S+S:
- Onset
- Bi/unilateral
- The actual symptoms
What about the reflexes?
What might happen in men?
Both - you get a mixed presentation
Sudden onset
Bilateral leg symptoms
Weakness
Perineal numbness
Urinary retention and faecal incontinence
Fasciculations
Hyperreflexic knee but hypo in others
Erectile dysfunction (ED)
Conus medullaris syndrome vs cauda equina syndrome:
- Which one tends to have less back pain but more radicular (dermatomal) pain?
- Which one has more ED, with sooner urinary retention?
- Which one has less fasciculations but more atrophy?
Cauda equina syndrome
Conus medullais syndrome
Cauda equina syndrome
Cauda equina syndrome:
Where is the lesion?
Presentation of symptoms:
- Sudden/gradual
- bi/unilateral
- sym/asymmetrical
Where is the numbness - 2
What about bowels and waterworks - 2
Reflexes?
Management - 1
Intradural roots and nerves below the spinal cord
Sudden or gradual onset
Bilateral
Asymmetrical leg symptoms
Saddle (upper inner thigh) and perineal numbness
Urinary retention and faecal incontinence
Hyporeflexia
Urgent neurosurgical decompression
Spine and nerve root anatomy:
Grey matter has a butterfly shape.
> What is in the dorsal horns and the ventral horns?
Surrounding white matter:
> What travels in the ascending tracts in the dorsal and external lateral cord?
> What travels in the descending tracts in the ventral and internal lateral cord?
D - sensory nuclei
V - motor nuclei
Sensory (afferent) info to the brain
Motor (efferent) info from the brain
Route of Spinal nerve:
What does the dorsal (back) root carry?
What does the ventral (front) root carry?
What does the anterior ramus innervate?
What does the posterior ramus innervate?
Why is it never wrong to scan too high in a suspected spinal cord lesion?
Sensory (afferent) information
Motor (efferent) information
Innervates most of the body
Innervates the back
Nerve roots move down alongside the spine before exiting the spinal cord - E.g T12 sensory level is at the level of the ASIS. even though it is far below the thoracic spine.
Radiculopathy:
This is nerve root compression.
Causes:
- Main causes
- Another 2 causes are spondylosis and spondylolisthesis?
Disc degeneration and herniation
Trauma
Veterbral degeneration
Veterbral displacement