Acute and Critical Care Flashcards
What is the threshold for immediate treatment of hyperkalaemia (with and without ECG changes)?
Serum potassium
- Greater than 6mmol/L with ECG changes
Greater than 6.5mmol/L without ECG changes
Cardiogenic causes of pulmonary oedema
Heart failure Myocarditis Tamponade Pulmonary embolism Valve disease NSAIDs, ACEi
Non-Cardiogenic causes of pulmonary oedema
AKI Renal artery stenosis Sepsis Altitude Liver failure Acute respiratory distress syndrome Head Injury
Symptoms of acute pulmonary oedema
SOB ± orthopnoea S3 sound Gallop rhythm Wheeze Pink frothy sputum Fine crackles Sweaty
Common infective organisms in COPD exacerbations
H. influenzae Strep pneumoniae Staph aureus Rhinovirus Influenzae
ECG findings in PE
Right Axis Deviation RBBB Tachycardia S1Q3T3 - Large S Wave in Lead 1 - Q wave in Lead 3 - Inverted T wave in Lead 3
PE Management (normal)
LMW Heparin or Fondaparinux
Aim for INR >2
Continue warfarin or NOAC for 3 months
Thrombolysis in PE
10mg IV Alteplase then 90mg infusion over 2 hours
PE Management in renal impairment
Unfractionated heparin
What score on the Two-Level Well’s Score suggests a PE is likely?
4 or more
less than 4 is PE unlikely
Management if PE likely on Two-Level Well’s Score
Offer CTPA, or immediate AC if CTPA not available immediately
V/Q SPECT scan if CTPA not suitable/ allergy to contrast media
Management if PE unlikely on Two-Level Well’s Score
Offer a D-Dimer
If positive, investigate as PE likely
Antibiotic management of mild Community acquired pneumonia
Amoxicillin
Antibiotic management of moderate CAP
Amoxicillin + Clarithromycin
Antibiotic management of severe CAP
Co-Amoxiclav/ Cephalosporin + Clarithromycin
Antibiotic management of HAP
Aminoglycoside IV + Antipseudomonal penicillin/ cephalosporin
Common CAP organisms
Strep pneumoniae
Haemophilus influenzae
Mycoplasma pneumoniae
Staph aureus
Common organisms in HAP
Gram negative enterobacteria S. aureus Pseudomonas aureginosa Klebsiella Clostridium
Symptoms of a silent MI
Syncope Pulmonary oedema/ SOB Epigastric pain Vomiting Acute confusion Feeling of impending doom Common in Elderly and diabetics
ECG changes in NSTEMI
ST depression
T wave inversion
No changes
Hyperacute changes in a STEMI
Tall T waves
Changes seen in a STEMI after hours (and the criteria for pPCI)?
ST elevation in 2 consanguineous leads - 2mm in chest leads - 1mm in limb leads New LBBB No evidence of a pathological Q wave
Latent ECG changes in a STEMI
T wave inversion
Contraindications to fibrinolysis
Previous intracranial haemorrhage Ischaemic stroke in last 6 months Cerebral malignancy Recent trauma or surgery in 3 weeks GI bleed in previous month Bleeding disorder Aortic dissection
Classification of Aortic Dissection
Type A- Affects the ascending aorta
Type B- affects other portion of aorta
Signs and symptoms of aortic dissection
Central retrosternal chest pain
- ‘Ripping’
- Radiates to back
- Worst at onset then gradually improves
Hemiplegia/ diplegia if carotid involvement
Limb ischaemia
Angina
Pulse deficit
Best imaging type for Aortic dissection
MRI
Management of aortic dissection
BP aim for 100-120 mmHg
Cross match 10 units of blood
Surgical (stents, grafts, arch replacement)
TEVAR for type B
Irregular features/ unstable in tachycardia warranting 3x DC shock followed by Amiodarone?
Hypotension/ shock Syncope HR >200BPM MI Heart failure Impaired consciousness
Examples of focal Narrow complex tachycardias
Sinus Tachycardia (underlying cause)
Atrial tachycardia
Junctional tachycardia
Multifocal atrial tachycardia
Condition in which Multifocal atrial tachycardias are common?
COPD
Examples of Re-entrant Narrow Complex Tachycardias
Atrial Flutter
Atrial Fibrillation
AV Node re-entry tachycardia
Atrio-Ventricular Re-entrant tachycardia
Management of Narrow complex tachycardia with IRREGULAR Rhythm
(Treat as Atrial Fibrillation)
Rate control with beta blocker or Diltiazem
± Digoxin or amiodarone if heart failure
LMW Heparin until full assessment of emboli risk ahs been made
Management of Narrow complex tachycardia with REGULAR rhythm
Vagal manoeuvres e.g. Valsalva, Carotid sinus massage
Adenosine 6mg rapid IV bolus
Followed by 2x12mg IV boluses if unsuccessful
Types of Broad complex tachycardia
Monomorphic (most common) Fascicular tachycardia RV outflow tract tachycardia Polymorphic tachycardia Torsade de pointes tachycardia
Management of Broad complex tachycardia with REGULAR rhythm
Amiodarone 300mg IV then 900mg/24h infusion
Management of Broad complex tachycardia with IRREGULAR rhythm
Depends on cause
- Torsade de pointes –> MgSO4 infusion 2g over 10 mins
Causes of bradyarrythmia/ complete heart block
Drugs (CCBs, Beta blockers, Digoxin)
Lenegre’s/ Lev’s disease
Severe hyperkalaemia
Management of bradyarrythmia with adverse features
Atropine 500mcg infusion every 3-5 minutes up to a maximum of 3mg
Percutaneous pacing/ pacemaker more definitive
Causes of VF
MI Cardiomyopathy aortic stenosis/ dissection myocarditis tamponade trauma Brudaga syndrome Tension pneumothorax PE Primary pulmonary hypertension QT Prolonging drugs Seizures Stroke Hyperkalaemia Sepsis Drowning Electrical shocks
Management of Ventricular Fibrillation
NON-Synchronised DC shock
Infective causes of pericarditis
Viral (Coxsackie virus, Echovirus, EBV, influenza, HIV)
Bacterial (staph, H. influenzae, TB, meningococcus, Rheumatic fever)
Other causes of pericarditis
Sarcoidosis SLE RA Vasculitis Myxoedema Uraemia Dressler's syndrome Radiotherapy
ECG findings of pericarditis
ST elevation (saddle-shaped) T wave inversion
Management of pericarditis
Ibuprofen or Naproxen 250mg QDS
Colchicine if symptoms persist for 14 days
Treat underlying cause ± steroids
AAA criteria for diagnosis
Dilation of the aorta of over 50% (usually 3cm original size)
Risk factors for AAA
Male (3x) Over 65 Smoking Hypertension COPD Alcohol Infective (Brucellosis, Salmonellosis, TB, HIV) Behcet's Disease Takayasu's Disease Marfan's Syndrome Ehlers-Danlos Syndrome
Criteria for surgical repair of AAA
Over 5.5cm in size
May be an open repair or endovascular (EVAR)
What percentage of appendicitis have perforated at presentation?
30%
What is Rovsing’s Sign in Appendicitis?
Pain is greater in the RIF when pressing the LIF
What is the Cope Sign in appendicitis?
Indicates a low appendix
Pain on flexion and internal rotation of the right hip
What indicates a retroperitoneal appendix?
Tenderness on the right on PR
RUQ and flank pain
Choice of antibiotics for Appendicitis?
Cefuroxime and Metronidazole pre-operatively
Biliary Colic presentation
RUQ pain radiating interscapularly
Nausea and vomiting
Intermittent jaundice
Lasts 15 mins to 24 hours
Biliary colic investigations
USS scan
Bloods unremarkable
ERCP/ CT/ MRI scans
Acute Cholecystitis presentation
RUQ pain radiating interscapularly Fever Local Peritonism (Murphy's Sign- pain when pressing right costal margin)
Nausea and vomiting
Intermittent jaundice
Acute cholecystitis investigation findings
USS scan
Bloods- mildly deranged LFTs, raised WCC/CRP
ERCP/ CT/ MRI scans
Cholangitis presentation
CHARCOT’S TRIAD
RUQ pain radiating interscapularly
Fever
Jaundice
Local Peritonism (Murphy’s Sign- pain when pressing right costal margin)
Cholangitis investigations findings
USS scan
Bloods- Raised WCC, CRP, ALP, GGT, Bilirubin
ERCP/ CT/ MRI scans
Risk factors for paralytic ileus
Surgery Pancreatitis Spinal injury Hypokalaemia Hyponatraemia Uraemia Peritoneal sepsis Drugs (TCAs)
AXR findings in small bowel obstruction
Distended loops of small bowel
Valvukae conniventes completely cross the lumen
AXR findings in large bowel obstruction
Haustra do not cross the bowel lumen
Coffee bean sign in sigmoid volvulus
Most common location of a diverticulum in adults
Sigmoid colon
Presentation of diverticulitis
LLQ colicky pain relieved on defaecation
Tenderness and peritonism
Fever
Sudden painless bleeding
Cullen’s sign in pancreatitis
Periumbilical bruising
Grey-Turner’s Sign in pancreatitis
Flank bruising
Serum enzyme measurements in pancreatitis
Amylase (usually increases 3x/ 1000u/mL; but may be normal even in severe disease)
Lipase (more sensitive and specific)
GET SMASHED acronym for causes of Pancreatitis
Gallstones
ETOH
Trauma
Steroids Mumps Auto-immune Scorpion Venom Hyperlipidaemia, Hypothermia, hypocalcaemia ERCP and emboli Drugs
And pregnancy or cancer!