Acute and Chronic Renal failure Flashcards
1
Q
what is acute renal failure
A
- inability for kidneys to excrete wastes, concentrate urine, and conserve electrolytes
2
Q
3 causes of acute kidney failure
A
- prerenal (decrease kidney perfusion)
- intrinsic renal (damage to kidney structures: glomeruli, tubules, vasculature)
- postrenal (obstruction)
3
Q
what are the prerenal causes of kidney failure
A
- dehydration (hypovolemia) from V/D
- DM
- surgical shock, trauma, burns
- accidental poisoning
- prolonged anesthesia
4
Q
what are the intrinsic renal causes of kidney failure
A
- ingestion of nephrotoxic medications
- hemolytic uremic syndrome, acute glomerulonephritis
- ischemia
5
Q
what are the postrenal causes of kidney failure
A
- kidney stones
- tumors
6
Q
what are the principle features of acute renal failure
A
- oliguria, azotemia ( increased urea and creatinine) -> leading to metabolic acidosis, electrolyte disturbances
7
Q
s/s of acute renal failure
A
- oliguria (<1mL/kg/hr)
- abrupt diuresis: sudden strong urge to urinate
- edema (pulmonary)
- circulatory collapse
- cardiac arrhythmia: hyperkalemia
- seizures: hyponatremia, hypocalcemia (tetany)
- tachypnea: metabolic acidosis
- CNS: from oliguria
8
Q
lab/diagnostics for acute renal failure
A
- electrolyte imbalances
- kidney panel: decreased urine creatinine, GFR, increased BUN
- metabolic acidosis
- anemia: low Hgb, Hct
- azotemia, increased blood creatinine
- EKG
- IVP (intravenous pyelogram: xray and contrast) & MRI for kidney function
9
Q
meds for acute kidney failure: hyperkalemia
A
- calcium gluconate
- sodium bicarbonate
- glucose and insulin IV
- sodium polystyrene sulfonate
10
Q
meds for acute kidney failure: antihypertensives
A
- labetalol or sodium nitroprusside
- hydralazine, clonidine, or verapamil
- captopril, minoxidil, propranolol, nifedipine, furosemide
vasodilators, beta blockers, ace inhibitors, loop diuretic
11
Q
treatment procedures for acute kidney failure
A
- dialysis (hemo or peritoneal)
- hemofiltration/ultrafiltration
12
Q
when does acute kidney failure becomes chronic
A
- diseased kidneys can’t maintain body needs
- half of renal capacity destroyed
- irreversible damage to nephrons, leading to uremia (toxin build up)
13
Q
potential causes of chronic kidney failure
A
- <5yrs: congenital, kidney & urinary tract malformations and vesicoureteral reflux
- 5+: VUR associated with recurrent UTIs, chronic pyelonephritis, chronic glomerulonephritis
14
Q
pathophysiology of chronic kidney failure
A
- waste products accumulate
- water & Na retention and decreased urine excretion -> edema
- high K, P
- low Na, Ca (P & Ca inverse relationship)
- decreased hydrogen secretion & bicarb reabsorption -> metabolic acidosis
- decreased erythropoietin from kidney, shortened PRBC lifespan -> anemia
15
Q
s/s of chronic kidney failure
A
- lethargy, fatigue
- pallor, bruising of skin
- delayed growth
- anorexia, N/V
- decreased urine output
- uremic odor from breath
- muscle cramps
- puffy face
- bone or joint pain
- amenorrhea
- circulatory overload: HTN, CHF, pulmonary edema
- neuro: tremors, twitching, confusion, seizures, coma