Acute Abdo Flashcards
What are the causes of abdominal perforation?
Stomach or duodenal ulcer Malignancy Fistula - crohns Infection - appendicitis, diverticulitis Ischaemia Obstruction Iatrogenic - anastomotic leak, endoscopy Trauma Direct - excessive vomiting
Name 2 signs on an X-Ray of perforation.
Rigler’s sign
Psoas sign
How might a retroperioneal perforation present?
R shoulder tip pain
Back pain
RIF pain - contents settles in paracolic gutter
What are the complications of perforation?
Infection - peritonitis + sepsis
Haemorrhage
What are signs of localised peritonitis?
Tender on palpation
Guarding
Rebound tenderness
May have systemic signs of infection
What are causes of localised peritonitis?
Appendicitis, Crohn’s disease, diverticulitis
Cholecystitis, salpingitis
What are signs of generalised peritonitis?
Abdomen rigid and tender
Cough test +ve
Bowel sends absent - peristalsis stopped
What causes generalised peritonitis?
Perforation of a viscus
What are the 2 types of generalised peritonitis?
Chemical - bile, stomach or small bowel contents
Bacterial - abscess rupture or faecal contamination from bowel, trauma, surgery or post-surgical leak
What is the management of generalised peritonitis?
High dose IV Abx
Urgent laparotomy to find cause and clear material ‘peritoneal toilet’
Describe the pathophysiology of pancreatitis.
Inflammation of pancreas.
Vascular permeability and fluid loss (3rd spacing)
Enzyme activation - tryptase
Fat necrosis by lipase, free FA react with calcium to form deposits (hypocalcaemia)
Enzymes can erode blood vessels -retroperitoneal bleeding
What are the causes of pancreatitis?
Iatrogenic/idiopathic Gallstones Ethanol Trauma Steroids Mumps Autoimmune - SLE Scorpion/snake bite Hypercalcaemia, hyperlipidaemia, hypothermia ERCP Drugs
Which drugs can cause pancreatitis?
Steroids
Azathioprine, antibiotics
NSAIDs
Diuretics
How does pancreatitis present?
Sudden onset severe, constant upper abdo pain. Radiates to back. Relieved sitting forward Vomiting Abdo distension
What are differential diagnosis for upper abdo pain radiating to the back?
Radiating to back:pancreatitis, ruptured AAA, dissecting aorta
Epigastric: peptic ulcer
Biliary colic cholecystitis
Pneumonia, Inferior MI
What investigations would you do in a patient with suspected pancreatitis?
FBC, U&E, CRP Amylase LFTs Lipase (if trust allows) ABG USS (unless obv cause)
What is important to remember about amylase?
- Levels do not correlate with disease severity
- Falls 24-48 hrs
Other than pancreatitis, what else can cause amylase to be raised?
Bowel perforation
Ectopic pregnancy
Mesenteric ischaemia
DKA
When should a CT scan be ordered in a patient with pancreatitis?
Only if not improved after 6-10 days and suspect complications such as necrosis.
If gallstone is found to be the cause of pancreatitis, what management should happen?
ERP and sphincterotomy within 72 hours.
What scale is used to grade the severity of pancreatitis?
Glasgow scale