Activation et polarisation des LT Flashcards

1
Q

TH1 - cytokines signalisation

A
  • IFN y
  • IL 12
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2
Q

TH1 - polarisation

A
  • transcription T Bet
  • S IFN y : action + intracel
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3
Q

TH2 - cytokines signalisation

A

IL4

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4
Q

TH2 - rôle

A

Allergie : PNE, PNB

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5
Q

TH2 - cytokines synthétisées

A
  • IL4
  • IL 5
  • IL 13
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6
Q

TH2 - pathologie

A

Lupus

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7
Q

TH17 - cytokines signalisation

A
  • IL 6
  • TGF B
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8
Q

TH17 - cytokines synthétisées

A
  • IL 2
  • IL 17
  • IL 22
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9
Q

TH17 - rôle

A

Action sur germes/bactéries extracel : PNN

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10
Q

TFH - rôle

A
  • Favorise maturation LB dans zone B ganglionnaire avec S Ig
  • Action sur tous types cellulaire
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11
Q

TFH - cytokines synthétisées

A
  • IL 4
  • IL 21
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12
Q

T reg - cyrokines signalisation

A
  • TGF B
  • IL 2
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13
Q

T reg - transcription

A

FOX P3

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14
Q

T reg - cytokines synthétisées

A
  • IL 10
  • TGF B
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15
Q

T reg - rôle

A

Regulation reaction immunitaire

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16
Q

TH17 - pathologie

A

Polyarthrite rhumatoïde

17
Q

T reg - pathologie

A

IPEX sd