Action potential Flashcards
Retinal ganglion cell responses
response from light against dark background, reacts to contrasts
Neuron
quiet in resting state
firing in action potential
Resting membrane potential
electrode measures potential, inside more -ve outside more +ve
ionic basis
K+ higher in cell NA+ higher outside neuron cell
electrostatic pressure
disperses positive and negative charges
ions pass through ion channels
3 pressures maintain unequal ion distribution
Electrochemical pressure
Concentration gradient
Sodium-potassium pump
electrostatic pressure
-ve attracts +ve (cations)
negative charge in cell repels negative charges in cell
concentration gradient
ions move from high to low concentration areas
sodium- potassium pump
pressure on Na+ to enter cell and K+ to exit
difficult as channels are almost shut but few do pass through
Action potential
excitation (-70 - -50mV) sodium channels open na+ rush in +50 mV K+ ions rush out channels close hyperpolarized
Polarized
resting state (-70mV)
Depolarized
action potential (+50mV)
repolarized
back to -70mV
Hyperolarized
drops below -70mV
refractory period
absolute - action potential cant happen milliseconds after first
relative - action potential only at high stimulation level