action potential Flashcards

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1
Q

what does a stimulus trigger

A

sodium ion channels to open

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2
Q

what is the first stage of generating an action potential

A

a stimulus excites the neuron causing sodium ion channels to open causing the membrane to become more permeable to Na+ ions

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3
Q

once sodium ion channels have been opened, what begins to happen

A

sodium ions diffuse into the neuron down their electrochemical gradient making the inside of the neuron less negative

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4
Q

what is the second stage of generating an action potential

A

depolarisation, when the potential difference reaches a threshold point (-55mv) voltage gated sodium ion channels open

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5
Q

what does the opening of voltage gated sodium channels cause

A

more sodium ions to diffuse into the neuron

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6
Q

what is the opening of voltage gated sodium channels an example of

A

positive feedback

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7
Q

what is the third stage of generating an action potential

A

repolarisation, at a potential difference of around +30mv, sodium ion channels close and voltage gated potassium channels open

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8
Q

what happen when potassium channels open

A

the membrane is more permeable to potassium ions causing them to diffuse out of the neuron down their concentration gradient

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9
Q

what is the purpose of the potassium channels opening

A

starts to restore a resting potential

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10
Q

what is the potassium channels opening an example of

A

negative feedback

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11
Q

what is hyperpolarisation

A

potassium ion channels have a delay in closing, this causes an overshoot of potassium out of the neuron causing the potential difference to be more negative than the resting potential

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12
Q

what happens after hyperpolarisation

A

the ion channels are reset and the sodium potassium pumps return the membrane to resting potential

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13
Q

what is the refractory period

A

after an action potential, ions cannot be stimulated as the ion channels are recovering and cannot open

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14
Q

what does a bigger stimulus cause

A

causes action potentials to fire more frequently

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15
Q

what is local currents

A

the influx of sodium ions into the neuron results in them diffusing and spreading out causing voltage gated sodium ion channels to open

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