action potential Flashcards
what does a stimulus trigger
sodium ion channels to open
what is the first stage of generating an action potential
a stimulus excites the neuron causing sodium ion channels to open causing the membrane to become more permeable to Na+ ions
once sodium ion channels have been opened, what begins to happen
sodium ions diffuse into the neuron down their electrochemical gradient making the inside of the neuron less negative
what is the second stage of generating an action potential
depolarisation, when the potential difference reaches a threshold point (-55mv) voltage gated sodium ion channels open
what does the opening of voltage gated sodium channels cause
more sodium ions to diffuse into the neuron
what is the opening of voltage gated sodium channels an example of
positive feedback
what is the third stage of generating an action potential
repolarisation, at a potential difference of around +30mv, sodium ion channels close and voltage gated potassium channels open
what happen when potassium channels open
the membrane is more permeable to potassium ions causing them to diffuse out of the neuron down their concentration gradient
what is the purpose of the potassium channels opening
starts to restore a resting potential
what is the potassium channels opening an example of
negative feedback
what is hyperpolarisation
potassium ion channels have a delay in closing, this causes an overshoot of potassium out of the neuron causing the potential difference to be more negative than the resting potential
what happens after hyperpolarisation
the ion channels are reset and the sodium potassium pumps return the membrane to resting potential
what is the refractory period
after an action potential, ions cannot be stimulated as the ion channels are recovering and cannot open
what does a bigger stimulus cause
causes action potentials to fire more frequently
what is local currents
the influx of sodium ions into the neuron results in them diffusing and spreading out causing voltage gated sodium ion channels to open