ACT Inf

Question 1

What causes Infectious Mononucleosis and how does it present?

Answer 1

Epstein-Barr virus

Classic triad:
Sore throat + Pyrexia + Lymphadenopathy

Others: Splenomegaly (50%)
Hepatitis, lymphocytosis, malaise, anorexia, headache
Haemolytic anaemia secondary to cold agglutins (IgM)

Question 2

Investigations for Infectious mononucleosis

Answer 2

FBC and Monospot test in the 2nd week of the illness to confirm a diagnosis of glandular fever.

Question 3

Management of infectious mononucleosis

Answer 3

Do NOT give amoxicillin or ampicillin
- a maculopapular, pruritic rash develops

Rest, Oral fluids, Analgesia
Avoid contact sports for 8 months
- due to risk of splenic rupture

Question 4

Management of MRSA colonisation positive screening on admission

Answer 4

Nose: Mupirocin 2% in white soft paraffin, tds for 5 days

Skin: Chlorhexidine gluconate, od for 5 days.
Apply all over but particularly to the axilla, groin and perineum