ACS Flashcards
Where do the coronary arteries come from?
Ascending aorta
Blockages of LCA lead to what?
CHF and left ventricle not pumping effectively
Blockages of RCA lead to what?
Right sided heart failure
Bradyarrhythmia due to SA node not getting blood
Left and right coronary veins drain their deoxygenated blood into what?
Coronary Sinus then to the Right atrium
So what’s the issue about Oxygen rich blood demand and myocardium?
Myocardium requires up to 65% O2, which does not allow much room for compensation if there is a reduction in blood flow.
normal tissues only require roughly 25%
What is Angina basically?
Chest pain caused by ischemia (myocardium isn’t getting enough O2)
Hallmarks of Stable Angina?
Pain only on exertion
Relieved by rest
Unstable Angina Hallmarks
Pain while resting
- Looks like NSTEMI
- Use cardiac markers to rule out MI
What is Prinzmetal’s Angina?
Caused by coronary vasospasm without any CAD
How can O2 delivery to the myocardium be increased?
Increase blood flow (Increase DBP or coronary dilation)
Decrease HR
What’s causing increased myocardial O2 demand?
Ventricular hypertrophy
Increased HR
Increased contractions
What falls under ACS?
Unstable Angina
NSTEMI
STEMI
Which MI is partial thickness infarction?
NSTEMI
Hallmark of NSTEMI?
Non-specific EKG or ST depression
Elevated Cardiac enzymes
Hallmark of STEMI
Both ST elevation and Cardiac enzymes
How can you tell the difference between a Prinzmetal Angina MI vs NSTEMI and STEMI?
Cardiac Catherization - no blockages in the coronary vessels
Will present with increased cardiac markers and ST elevations/depressions
What is a suspicious cause of NSTEMI or STEMI for young individuals with no risk factors?
Cocaine use - causes severe vasoconstriction
What’s your hallmarks for MI?
SUBSTERNAL CHEST PAIN Elephant on your chest Radiation Pain at rest New Heart Murmur Mitral Regurg S3 for LV - overload CHF
Levine’s sign
- Anxious
- Diaphoretic
- Clinched fist over chest
Pulse will depend on location of infarction why?
RCA - SA lack of perfussion leads to bradycardia
LCA - tachy and CHF
Labs for MI?
Troponin CK-MB EKG Chest X-ray for CHF Echo Cardiac Catheterization
Treatment for MI
PREVENT further cardiac damage
ABCs, Monitor, O2, IV
ONAM
- O2
- Nitro - 0.4mg sublingual q 5 min for angina
- Aspirin - 325mg chew
- Morphine - 4mg IV for unresponsive to nitro