Acronyms Flashcards

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1
Q

cDNA

A

complementary DNA

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2
Q

PCR

A

polymerase chain reaction

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3
Q

ORF

A

open reading frame

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4
Q

SCID

A

severe combined immune disease

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5
Q

ccccDNA

A

covalently closed circular extrachromosomal DNA

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6
Q

BAC

A

bacterial artificial chromosome

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7
Q

RF

A

recombination frequency

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8
Q

m.u.

A

mapping unit

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9
Q

cM

A

centiMorgan

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10
Q

I

A

interference

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11
Q

coc

A

coefficient of coincidence

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12
Q

SNPs

A

single nucleotide polymorphisms

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13
Q

RFLPs

A

restriction fragment length polymorphisms

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14
Q

SSLPs

A

single sequence length polymorphisms

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15
Q

VNTRs

A

variable number of tandem repeats

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16
Q

kb

A

kilobases

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17
Q

LOD

A

log of odds

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18
Q

Hb

A

Hemoglobin allele

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19
Q

tRNA

A

transfer RNA

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20
Q

P

A

parental generation

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21
Q

F1/F2

A

filial generation

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22
Q

TDF

A

testis determining factor (ie. SRY gene)

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23
Q

SRY

A

sex-determining region on the Y chromosome

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24
Q

AD

A

autosomal dominant inheritance

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25
Q

AR

A

autosomal recessive inheritance

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26
Q

PKU

A

phenylketonuria

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27
Q

CF

A

cystic fibrosis

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28
Q

MERRF

A

myoclonic epilepsy and ragged red fiber

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29
Q

LHON

A

Leber’s hereditary optic neuropathy

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30
Q

CpG

A

Cytosine-phosphate-Guanine

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31
Q

INDEL

A

insertion/deletion mutations

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32
Q

SNoW
DRoP

A

Southern blotting = DNA
Northern blotting = mRNA
Western blotting = Protein

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33
Q

EMS

A

Ethylmethane sulfonate

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34
Q

2-AP

A

2-aminopurine

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35
Q

5-BU

A

5-bromouracil

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36
Q

AFB1

A

aflatoxin B1

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37
Q

XP

A

Xeroderma Pigmentosa

38
Q

HNPCC

A

Hereditary Non-polyposis colon cancer

39
Q

I (operon)

A

repressor

40
Q

P (operon)

A

Promotor

41
Q

O

A

operator

42
Q

Z

A

B-galactosidase

43
Q

Y

A

permease

44
Q

A

A

transacetylase

45
Q

CAP

A

catabolite activator protein

46
Q

cAMP

A

cyclic adenosine monophosphate

47
Q

IPTG

A

isopropyl-Beta-D-1-thiogalactopyranoside

48
Q

C

A

arabinose repressor/activator

49
Q

araC

A

arabinose protein repressor/activator

50
Q

B, A, D

A

enzymes for arabinose metabolism

51
Q

L

A

leader (in tryptophan operon)

52
Q

trp

A

tryptophan

53
Q

lac

A

lactose

54
Q

UPE

A

upstream promotor elements

55
Q

TSS

A

transcription start site

56
Q

ssDNA

A

single-stranded DNA

57
Q

rRNA

A

ribosomal RNA

58
Q

snRNA

A

small nuclear RNA

59
Q

miRNA

A

microRNA

60
Q

siRNA

A

small interfering RNA

61
Q

UTR

A

untranslated region

62
Q

GTF

A

general transcription factors

63
Q

PIC

A

pre-initiation complex

64
Q

TBP

A

TATA binding protein

65
Q

CTD

A

carboxy terminal domain

66
Q

poly-A

A

polyadenylation (AAAAAAAA…)

67
Q

PAP

A

Poly(A) polymerase

68
Q

AUG

A

methionine (start codon)

69
Q

UGG

A

tryptophan

70
Q

AUA

A

methionine (in mitochondrial DNA)

71
Q

UGA

A

stop codon
tryptophan (in mitochondrial DNA)

72
Q

UUU

A

phenylalanine (poly(U))

73
Q

UAG

A

stop codon

74
Q

UAA

A

stop codon

75
Q

AA

A

amino acid

76
Q

DHU

A

dihydrouridine

77
Q

mI

A

methylinosine

78
Q

I (base)

A

inosine

79
Q

mG

A

methylguanosine

80
Q

aa-tRNA

A

aminoacyl-tRNA (charged tRNA)

81
Q

S

A

Svedbergs

82
Q

A (binding site)

A

aminoacyl

83
Q

P (binding site)

A

peptidyl

84
Q

E (binding site)

A

exit

85
Q

EF-Tu, EF-Ts, EF-G

A

translation elongation factors

86
Q

XLR

A

X-linked recessive

87
Q

XLD

A

X-linked dominant

88
Q

YL

A

Y-linked

89
Q

SSBP

A

single-stranded binding protein

90
Q

dNTP

A

deoxy-nucleoside-tri-phosphate