Acronyms Flashcards
cDNA
complementary DNA
PCR
polymerase chain reaction
ORF
open reading frame
SCID
severe combined immune disease
ccccDNA
covalently closed circular extrachromosomal DNA
BAC
bacterial artificial chromosome
RF
recombination frequency
m.u.
mapping unit
cM
centiMorgan
I
interference
coc
coefficient of coincidence
SNPs
single nucleotide polymorphisms
RFLPs
restriction fragment length polymorphisms
SSLPs
single sequence length polymorphisms
VNTRs
variable number of tandem repeats
kb
kilobases
LOD
log of odds
Hb
Hemoglobin allele
tRNA
transfer RNA
P
parental generation
F1/F2
filial generation
TDF
testis determining factor (ie. SRY gene)
SRY
sex-determining region on the Y chromosome
AD
autosomal dominant inheritance
AR
autosomal recessive inheritance
PKU
phenylketonuria
CF
cystic fibrosis
MERRF
myoclonic epilepsy and ragged red fiber
LHON
Leber’s hereditary optic neuropathy
CpG
Cytosine-phosphate-Guanine
INDEL
insertion/deletion mutations
SNoW
DRoP
Southern blotting = DNA
Northern blotting = mRNA
Western blotting = Protein
EMS
Ethylmethane sulfonate
2-AP
2-aminopurine
5-BU
5-bromouracil
AFB1
aflatoxin B1