Acne Flashcards

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1
Q

What is acne vulgaris?

A

Chronic inflammatory disease of pilosebaceous unit

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2
Q

Prime age for acne in males vs females

A
Males = 16-19
Females = 14-17
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3
Q

Pathogenesis of acne

A

Poral occlusion
Bacterial occlusion of duct
Dermal inflammation
Increased sebum production

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4
Q

Distribution of acne vulgaris

A

Related to the sites with the most sebaceous glands - face, upper back, anterior chest

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5
Q

Morphology of acne vulgaris

A

Comedones (open = blackhead, closed = whitehead)
Pustules and papules
Cysts
Erythema

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6
Q

Secondary features of acne vulgaris

A

Scars - atrophic, ice pick, texture changes, hypertrophic

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7
Q

Acne grading

A

Mild - scattered papules and pustules, comedones
Moderate - numerous papules and pustules, mild atrophic scarring
Severe - cysts, nodules, significant scarring

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8
Q

Treatment for acne

A
Aim to control/prevent acne
Most will spontaneously resolve over time
Avoid oily substances/triggers
Topical treatment
Systemic treatment
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9
Q

Topical treatment for acne

A

Benzoyl peroxide - keratolytic, antibacterial
Topical vitamin A derivatives - drying effect
Topical antibiotics - antibacterial and anti-inflammatory

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10
Q

Systemic treatment for acne

A

Antibiotics - antibacterial and anti-inflammatory

Isotretinoin (oral retinoid) - effect on sebaceous gland activity but lots of side effects including initial aggravation

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11
Q

How many lesions are there in mild to moderate acne?

A

<30

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12
Q

How many lesions are there in severe cystic acne with scarring?

A

> 125 lesions

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