Acne Flashcards

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1
Q

Acne Vulgaris

A

inflammatory condition - lesions develop from sebaceous glands around hair follicles on face, chest, back.

Typically starts in teenage years but often self limiting

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2
Q

Acne Rosacea

A

Inflammatory papules, pustules and erythema

- no comedones

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3
Q

when is Isotretinoin recommended

A

when pt has inflammatory papules + comedones that fail to respond to topical retinoid and oral AB fro 3 months

Moderate acne - unresponsive to conventional therapy or relapsing severe acne

acne scarring

psychological effects resulting from acne + scarring

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4
Q

management of mild acne

A

1st line = topical trx - benzoyl peroxide

2nd line = topical retinoids

3rd line = azelaic acid

  • consider OCP
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5
Q

what can worsen acne (2)

A
  • anabolic steroids

- menstruation

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6
Q

name 6 types of acne

A
  • acne vulgaris
  • acne rosacea
  • acne exoriee
  • infantile acne
  • acne conglobata
  • pyoderma faciale
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7
Q

Pyroderma faciale

A
  • starts abruptly
  • lasts < 1 yera
  • confined to face
  • not assoc w/ oily skin
  • only women
  • not linked to comedones
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8
Q

causes of acne exoriee

A

scratching, picking, squeezing

leading to; bleeding, oozing pus, deep scarring of skin

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9
Q

acne Congloblata

A
  • severe form
  • boys + tropical areas
  • face + limbs
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10
Q

visual characteristics of acne rosacea?

A
  • erythema w/ prominent blood vessels
  • pustules
  • papules
  • oedema
  • persistent erruption
  • assoc w/ flushing
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11
Q

Inflammatory condition where lesions develop from sebaceous glands around hair follicles

A

acne vulgaris

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12
Q

sebaceous glands produce ___ in acne vulgaris

A

excess grease

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13
Q

how are comedones produced in acne vulgaris

A

thickening of the keratin lining of sebaceous duct

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14
Q

validated scoring system to assess affect of disease on person

A

APSEA

assessment of psychological + social effect of acne

consists of 15 questions

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15
Q

what is Leeds scoring system

A

counts + categorises lesions into inflammatory and non inflammatory ranging from 0 –> 12

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16
Q

epidemiology of acne vulgaris

A

80-90% teenagera

17
Q

comedones are due to

A

dilated sebaceous follicle

18
Q

how to inflammatory lesions: papules + pustules form?

A

when follicle bursts, releasing irritants

19
Q

scars formed in acne vulgaris (2)

A
  • ice pick scars

- hypertrophic scars

20
Q

symptoms that lead to suspecting PCOS
+
Investigation

A
  • oligomenorrhoe + hirstuism

- free testosterone levels

21
Q

step 1 - treatment of comedonal acne

A

1st line - topical retinoid e.g. differin

2nd line - azelaic acid

22
Q

step 2 - trx mild to moderate papular/pustular acne

A

ideally containing benzoyl peroxide w/ topical retinoid OR topical abx

e. g.:
- epiduo gel
- Duac: clindamycin + BPO

23
Q

role of BPO

A

reduce bacterial resistance

24
Q

step 3 trx

A

combine systemic abx + topical agent

25
Q

systemic antibiotics (3)

A
  • tetracyclines
  • macrolides
  • trimethoprim
26
Q

1st line abx choice

A

tetracyclines

27
Q

hormonal trx

A

co - cyprindiol

contains an anti androgen that decreases sebum secretion

28
Q

mechanism of isotretinoin

A

reduces sebum production

29
Q

SE isotretinoin

A
  • skin+mucous membrane dryness
  • nose bleeds
  • joint pains
  • teratogenic
  • psychiatric changes
30
Q

management of hypertrophic/keloid scars

A

silicone gel

31
Q

typically affected areas by acne rosacea

A
  • forehead
  • cheeks
  • nose
32
Q

management of mild symptoms of acne rosacea

A

topical metronidazole, azelic acid, topical ivermectin

33
Q

management of prominent telengiectasia in acne rosacea

A

laser therapy

34
Q

management of facial erythema in rosacea

A

brimonidine tartrate