Acne Flashcards
What is the maximum cumulative dose for isotretanoin in mg/kg?
120-150mg/kg
How long should the 1st line option for acne be trialled before reviewing?
12 weeks
When should isotretanoin be considered as a treatment option for acne?
Tbc
What are the 1st line treatment options for acne of any severity?
Topical:
Adapalene with benzyl peroxide
Tretinoin with clindamycin
Which acne treatment options can cause photosensitivity?
All
What is the normal daily dose of isotretinoin?
0.5-1mg/kg
Most people are on 20-80mg OD
How long is an isotretinoin prescription valid for?
7 days
What blood tests are required before and during isotretinoin treatment?
Lipids and LFTs
What is 1st line treatment for mild/moderate acne?
Topical:
Benzylperixide with clindamycin
Which of the 1st line treatments for acne can be used in pregnancy?
Topical Benzoyl peroxide with topical clindamycin
What are the common side effects of isotretinoin?
Dry skin, eyes, lips (leading to infections)
Eye inflammation/infections
Back pain
Skin fragility
Joint stiffness
Altered mood
Reddened skin and other skin reactions
What acne treatment should be offered to individuals with PCOS if the chosen 1st line option has failed?
Addition of ethinylestradiol with cyproterone acetate (co-cyprindiol) or an alternative COC to their treatment
Review at 6 months
When prescribing isotretinoin for a women, when should the pregnancy test be carried out?
The same day ideally (not legally)
What is the dosing for doxycycline and lymecycline for acne treatment?
Doxycycline: 100mg OD
Lymecycline: 408mg OD
What drugs are contraindicated with isotretinoin?
Tetracyclines
Methotrexate
Vitamin A supplements
