Acids, bases and buffers Flashcards
1
Q
Describe the law of mass action.
A
- For a reversible reaction, the forward and reverse rates of the reaction are directly dependent on the concentration of reactants and products
- Keq = [products]/[reactants]
2
Q
Keq of water
A
1.8 x 10-16
3
Q
[H+][OH-] = ?
A
1 x 10-14
4
Q
How strong is the acids when the pKa is low?
A
stronger the acid
5
Q
What is the Henderson-Hasselbalch equation?
A
pH = pKa + log([A-]/[HA])
when pH = pKa then the concentrations of deprotonation and protonation acid are equal
6
Q
What is the H-H equation for the bicarbonate buffer system in extracellular fluid?
A
pH = 6.1 + log ([HCO3-]mM/ 0.03 * CO2 mmHg)
7
Q
Normal pH for arterial blood
A
7.34 - 7.44
8
Q
Normal pH for venous blood
A
7.28 - 7.42
9
Q
Normal concentration of HCO3- in blood
A
24 mM
10
Q
Normal pCO2 in blood
A
40 mmHg
11
Q
Normal concentration of Co2 in blood
A
1.2 mM
12
Q
High pKa means a strong/weak acid/base?
A
strong base
