Acidosis_and_Alkalosis_Full_Flashcards

1
Q

What is the normal range of systemic arterial pH?

A

7.35 to 7.45.

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2
Q

Which organs are primarily responsible for maintaining acid-base homeostasis?

A

Lungs and kidneys.

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3
Q

What is the role of the kidneys in regulating plasma bicarbonate levels?

A

Regulate acid-base balance by reabsorbing or excreting bicarbonate.

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4
Q

What condition results from the underexcretion of CO2?

A

Hypercapnia.

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5
Q

What is the typical steady-state value for PaCO2?

A

40 mmHg.

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6
Q

How is the Henderson-Hasselbalch equation used in acid-base disorders?

A

It describes the relationship between bicarbonate and CO2 to determine pH.

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7
Q

What does an elevated anion gap indicate?

A

The presence of unmeasured anions in the blood.

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8
Q

Name two major categories of metabolic acidosis.

A

High-anion gap and normal-anion gap.

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9
Q

What is Winter’s equation used for?

A

To predict the expected PaCO2 in metabolic acidosis.

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10
Q

What is the compensation pattern in metabolic alkalosis?

A

Increased PaCO2 by 0.75 mmHg per mmol/L increase in HCO3-.

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11
Q

List three causes of hyperchloremic metabolic acidosis.

A

Diarrhea, renal tubular acidosis, external pancreatic drainage.

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12
Q

What are the clinical features of metabolic acidosis?

A

Kussmaul respiration, CNS depression, cardiac depression.

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13
Q

How does vomiting cause metabolic alkalosis?

A

Loss of HCl from gastric secretions increases serum bicarbonate.

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14
Q

What are mixed acid-base disorders?

A

Coexisting acid-base disorders not explained by compensation.

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15
Q

What is the treatment for high-anion gap metabolic acidosis due to lactic acidosis?

A

Correct underlying cause, restore perfusion, and administer NaHCO3 for severe acidemia.

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16
Q

Define respiratory acidosis.

A

Elevated PaCO2 and decreased pH.

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17
Q

What is the hallmark of respiratory alkalosis?

A

Low PaCO2 due to hyperventilation.

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18
Q

What conditions can cause a high-anion gap metabolic acidosis?

A

Lactic acidosis, ketoacidosis, renal failure, ingested toxins.

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19
Q

What are the treatment goals for diabetic ketoacidosis (DKA)?

A

Restore volume, correct acidosis, and administer insulin.

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20
Q

What are two main types of lactic acidosis?

A

Type A (poor perfusion) and Type B (metabolic disorders).

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21
Q

What is the normal range of systemic arterial pH?

A

7.35 to 7.45.

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22
Q

Which organs are primarily responsible for maintaining acid-base homeostasis?

A

Lungs and kidneys.

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23
Q

What is the role of the kidneys in regulating plasma bicarbonate levels?

A

Regulate acid-base balance by reabsorbing or excreting bicarbonate.

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4
5
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24
Q

What condition results from the underexcretion of CO2?

A

Hypercapnia.

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25
Q

What is the typical steady-state value for PaCO2?

A

40 mmHg.

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26
Q

How is the Henderson-Hasselbalch equation used in acid-base disorders?

A

It describes the relationship between bicarbonate and CO2 to determine pH.

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27
Q

What does an elevated anion gap indicate?

A

The presence of unmeasured anions in the blood.

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28
Q

Name two major categories of metabolic acidosis.

A

High-anion gap and normal-anion gap.

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29
Q

What is Winter’s equation used for?

A

To predict the expected PaCO2 in metabolic acidosis.

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30
Q

What is the compensation pattern in metabolic alkalosis?

A

Increased PaCO2 by 0.75 mmHg per mmol/L increase in HCO3-.

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31
Q

List three causes of hyperchloremic metabolic acidosis.

A

Diarrhea, renal tubular acidosis, external pancreatic drainage.

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32
Q

What are the clinical features of metabolic acidosis?

A

Kussmaul respiration, CNS depression, cardiac depression.

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33
Q

How does vomiting cause metabolic alkalosis?

A

Loss of HCl from gastric secretions increases serum bicarbonate.

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3
4
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34
Q

What are mixed acid-base disorders?

A

Coexisting acid-base disorders not explained by compensation.

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35
Q

What is the treatment for high-anion gap metabolic acidosis due to lactic acidosis?

A

Correct underlying cause, restore perfusion, and administer NaHCO3 for severe acidemia.

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36
Q

Define respiratory acidosis.

A

Elevated PaCO2 and decreased pH.

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37
Q

What is the hallmark of respiratory alkalosis?

A

Low PaCO2 due to hyperventilation.

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38
Q

What conditions can cause a high-anion gap metabolic acidosis?

A

Lactic acidosis, ketoacidosis, renal failure, ingested toxins.

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39
Q

What are the treatment goals for diabetic ketoacidosis (DKA)?

A

Restore volume, correct acidosis, and administer insulin.

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40
Q

What are two main types of lactic acidosis?

A

Type A (poor perfusion) and Type B (metabolic disorders).

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41
Q

What is the normal range of systemic arterial pH?

A

7.35 to 7.45.

42
Q

Which organs are primarily responsible for maintaining acid-base homeostasis?

A

Lungs and kidneys.

43
Q

What is the role of the kidneys in regulating plasma bicarbonate levels?

A

Regulate acid-base balance by reabsorbing or excreting bicarbonate.

44
Q

What condition results from the underexcretion of CO2?

A

Hypercapnia.

45
Q

What is the typical steady-state value for PaCO2?

46
Q

How is the Henderson-Hasselbalch equation used in acid-base disorders?

A

It describes the relationship between bicarbonate and CO2 to determine pH.

47
Q

What does an elevated anion gap indicate?

A

The presence of unmeasured anions in the blood.

48
Q

Name two major categories of metabolic acidosis.

A

High-anion gap and normal-anion gap.

49
Q

What is Winter’s equation used for?

A

To predict the expected PaCO2 in metabolic acidosis.

50
Q

What is the compensation pattern in metabolic alkalosis?

A

Increased PaCO2 by 0.75 mmHg per mmol/L increase in HCO3-.

51
Q

List three causes of hyperchloremic metabolic acidosis.

A

Diarrhea, renal tubular acidosis, external pancreatic drainage.

52
Q

What are the clinical features of metabolic acidosis?

A

Kussmaul respiration, CNS depression, cardiac depression.

53
Q

How does vomiting cause metabolic alkalosis?

A

Loss of HCl from gastric secretions increases serum bicarbonate.

54
Q

What are mixed acid-base disorders?

A

Coexisting acid-base disorders not explained by compensation.

55
Q

What is the treatment for high-anion gap metabolic acidosis due to lactic acidosis?

A

Correct underlying cause, restore perfusion, and administer NaHCO3 for severe acidemia.

56
Q

Define respiratory acidosis.

A

Elevated PaCO2 and decreased pH.

57
Q

What is the hallmark of respiratory alkalosis?

A

Low PaCO2 due to hyperventilation.

58
Q

What conditions can cause a high-anion gap metabolic acidosis?

A

Lactic acidosis, ketoacidosis, renal failure, ingested toxins.

59
Q

What are the treatment goals for diabetic ketoacidosis (DKA)?

A

Restore volume, correct acidosis, and administer insulin.

60
Q

What are two main types of lactic acidosis?

A

Type A (poor perfusion) and Type B (metabolic disorders).

61
Q

What is the normal range of systemic arterial pH?

A

7.35 to 7.45.

62
Q

Which organs are primarily responsible for maintaining acid-base homeostasis?

A

Lungs and kidneys.

63
Q

What is the role of the kidneys in regulating plasma bicarbonate levels?

A

Regulate acid-base balance by reabsorbing or excreting bicarbonate.

64
Q

What condition results from the underexcretion of CO2?

A

Hypercapnia.

65
Q

What is the typical steady-state value for PaCO2?

66
Q

How is the Henderson-Hasselbalch equation used in acid-base disorders?

A

It describes the relationship between bicarbonate and CO2 to determine pH.

67
Q

What does an elevated anion gap indicate?

A

The presence of unmeasured anions in the blood.

68
Q

Name two major categories of metabolic acidosis.

A

High-anion gap and normal-anion gap.

69
Q

What is Winter’s equation used for?

A

To predict the expected PaCO2 in metabolic acidosis.

70
Q

What is the compensation pattern in metabolic alkalosis?

A

Increased PaCO2 by 0.75 mmHg per mmol/L increase in HCO3-.

71
Q

List three causes of hyperchloremic metabolic acidosis.

A

Diarrhea, renal tubular acidosis, external pancreatic drainage.

72
Q

What are the clinical features of metabolic acidosis?

A

Kussmaul respiration, CNS depression, cardiac depression.

73
Q

How does vomiting cause metabolic alkalosis?

A

Loss of HCl from gastric secretions increases serum bicarbonate.

74
Q

What are mixed acid-base disorders?

A

Coexisting acid-base disorders not explained by compensation.

75
Q

What is the treatment for high-anion gap metabolic acidosis due to lactic acidosis?

A

Correct underlying cause, restore perfusion, and administer NaHCO3 for severe acidemia.

76
Q

Define respiratory acidosis.

A

Elevated PaCO2 and decreased pH.

77
Q

What is the hallmark of respiratory alkalosis?

A

Low PaCO2 due to hyperventilation.

78
Q

What conditions can cause a high-anion gap metabolic acidosis?

A

Lactic acidosis, ketoacidosis, renal failure, ingested toxins.

79
Q

What are the treatment goals for diabetic ketoacidosis (DKA)?

A

Restore volume, correct acidosis, and administer insulin.

80
Q

What are two main types of lactic acidosis?

A

Type A (poor perfusion) and Type B (metabolic disorders).

81
Q

What is the normal range of systemic arterial pH?

A

7.35 to 7.45.

82
Q

Which organs are primarily responsible for maintaining acid-base homeostasis?

A

Lungs and kidneys.

83
Q

What is the role of the kidneys in regulating plasma bicarbonate levels?

A

Regulate acid-base balance by reabsorbing or excreting bicarbonate.

84
Q

What condition results from the underexcretion of CO2?

A

Hypercapnia.

85
Q

What is the typical steady-state value for PaCO2?

86
Q

How is the Henderson-Hasselbalch equation used in acid-base disorders?

A

It describes the relationship between bicarbonate and CO2 to determine pH.

87
Q

What does an elevated anion gap indicate?

A

The presence of unmeasured anions in the blood.

88
Q

Name two major categories of metabolic acidosis.

A

High-anion gap and normal-anion gap.

89
Q

What is Winter’s equation used for?

A

To predict the expected PaCO2 in metabolic acidosis.

90
Q

What is the compensation pattern in metabolic alkalosis?

A

Increased PaCO2 by 0.75 mmHg per mmol/L increase in HCO3-.

91
Q

List three causes of hyperchloremic metabolic acidosis.

A

Diarrhea, renal tubular acidosis, external pancreatic drainage.

92
Q

What are the clinical features of metabolic acidosis?

A

Kussmaul respiration, CNS depression, cardiac depression.

93
Q

How does vomiting cause metabolic alkalosis?

A

Loss of HCl from gastric secretions increases serum bicarbonate.

94
Q

What are mixed acid-base disorders?

A

Coexisting acid-base disorders not explained by compensation.

95
Q

What is the treatment for high-anion gap metabolic acidosis due to lactic acidosis?

A

Correct underlying cause, restore perfusion, and administer NaHCO3 for severe acidemia.

96
Q

Define respiratory acidosis.

A

Elevated PaCO2 and decreased pH.

97
Q

What is the hallmark of respiratory alkalosis?

A

Low PaCO2 due to hyperventilation.

98
Q

What conditions can cause a high-anion gap metabolic acidosis?

A

Lactic acidosis, ketoacidosis, renal failure, ingested toxins.

99
Q

What are the treatment goals for diabetic ketoacidosis (DKA)?

A

Restore volume, correct acidosis, and administer insulin.

100
Q

What are two main types of lactic acidosis?

A

Type A (poor perfusion) and Type B (metabolic disorders).