acid-base imbalances Flashcards
what disease processes commonly have acid-base imbalances?
diabetes, COPD, kidney disease, vomiting and diarrhea, hypoxia
what group has the toughest time compensating for imbalances?
older adult - decreasing function of renal and rest systems
what 3 mechanisms regulate pH?
- buffers (convert strong acid to weak acid, neutralize bases)
- respiratory system (removes CO2 and water)
- renal system (kidneys reabsorb bicarbonate, eliminate hydrogen ions)
how long does it take for buffers to act?
immediately
how long does it take for the respiratory system to act?
responds in minutes
how long does it take for the renal system to act?
2-3 days
which substance does the body buffer more effectively?
acids over bases
how does the respiratory system regulate imbalances?
through hyper and hypoventilation (removal or conservation of CO2)
what acid or base does respiratory compromise?
CO2
what acid or base does metabolic compromise?
HCO3
how is acidosis caused?
- increase in CO2
- decrease in HCO3
how is alkalosis caused?
- decrease in CO2
- increase in HCO3
respiratory acidosis
- CO2 retention from hypoventilation
- compensatory réponse to HCO3 retention by kidneys
- increased carbonic acid
respiratory alkalosis
- increased CO2 excretion from hyperventilation
- compensatory response to HCO3 excretion by kidneys
- decreased carbonic acid
metabolic acidosis
- gain of fixed acid, inability to excrete acid
- compensatory response of CO2 excretion by lungs
- bicarbonate deficiency