Acid-Base Disorders Flashcards

1
Q

Rules to approach acid-base disorders

A
  1. Look at pH.
  2. Calc. anion gap
  3. Calc. osmol. gap if anion gap elevated
  4. Calc. excess anion gap
  5. Interpret data using clinical picture
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2
Q

Rules to approach acid-base disorders

A
  1. Look at pH.
  2. Calc. anion gap
  3. Calc. osmol. gap if anion gap elevated
  4. Calc. excess anion gap
  5. Interpret data using clinical picture
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3
Q

Anion gap calculation

A

Na+ - (HCO3- + Cl-)

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4
Q

Normal anion gap

A

12

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5
Q

Osmol gap calculation

A

Measured osmolarity- calculated osms

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6
Q

Normal osmol gap

A
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7
Q

Calculated osms equation

A

(2Na+) + (Glucose/18) + (BUN/2.8)

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8
Q

Normal calculated osms

A

Usually around 285

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9
Q

Normal excess anion gap (Delta gap)

A

24-26

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10
Q

Normal excess anion gap

A

24-26

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11
Q

What if excess anion gap is low or high?

A

Low: non-anion gap acidosis.
High: metabolic alkalosis

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12
Q

What is the normal drop in bicarb per change of anion gap

A

Change of anion gap of 1 will drip HCO3- by equal amount

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13
Q

Anion gap calculation

A

Na+ - (HCO3- + Cl-)

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14
Q

Normal anion gap

A

12

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15
Q

Osmol gap calculation

A

Measured osmolarity- calculated osms

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16
Q

Normal osmol gap

A
17
Q

Calculated osms equation

A

(2Na+) + (Glucose/18) + (BUN/2.8)

18
Q

Normal calculated osms

A

Usually around 285

19
Q

Excess anion gap calculation

A

(Anion gap - 12) + measured bicarb

20
Q

Normal excess anion gap

A

24-26

21
Q

What if excess anion gap is low or high?

A

Low: non-anion gap acidosis.
High: metabolic alkalosis

22
Q

What is the normal drop in bicarb per change of anion gap

A

Change of anion gap of 1 will drip HCO3- by equal amount