Acid/Base Balance + Blood Flow Flashcards
Increase RBF
Increase GFR
Dilation of Afferent
Constriction of both Afferent and Efferent
Decrease RBF
No effect on GFR
Constrict Afferent
Decrease GFR in response to high RBF (high BP)
PCO2 less than 40
Respiratory Alkalosis
Compensatory: Decrease bicarb reabsorption
Decrease H+ secretion as well
Acetazolamide - inhibit Carbonic Anhydrase
HCO3- less than 24
Metabolic Acidosis
Compensatory: Decrease PCO2
Increase Ventilation Rate
Dilation of Afferent
Increase RBF
Increase GFR
Increase RBF
No effect on GFR
Dilation of both Afferent and Efferent
Increase RBF
Decrease GFR
Dilation of Efferent
Constrict Efferent
Increases GFR, but only due to a decreased RBF
AngII - increases filtration and reabsorption in the proximal tubule
Decrease RBF
No effect on GFR
Constriction of both Afferent and Efferent
Dilation of Efferent
Increase RBF
Decrease GFR
Dilation of both Afferent and Efferent
Increase RBF
No effect on GFR
PCO2 greater than 40
Respiratory Acidosis
Compensatory: Reabsorb more bicarb
Stimulate H+ secretion as well
HCO3- greater than 24
Metabolic Alkalosis
Compensatory: Increase PCO2
Decrease Ventilation Rate
Atonic Bladder
Destruction of sensory nerve fibers
Insensitive to stretch
OVERFLOW INCONTINENCE
Automatic Bladder
Spinal Cord damage above the Sacrum
Inhibits CENTRAL CONTROL of reflexes
Uncontrolled and unannounced bladder emptying
Uninhibited Neurogenic Bladder
Interruption of INHIBITORY SIGNALS
Frequent small volumes of urine
At risk for UTI’s
Interruption of INHIBITORY SIGNALS
Uninhibited Neurogenic Bladder
Inhibition of CENTRAL CONTROL of reflexes
Automatic Bladder
Destruction of Sensory Nerve fibers
Atonic Bladder
Overflow incontinence
Small frequent volumes of urine
Uninhibited neurogenic bladder
Uncontrolled and unannounced bladder emptying
Automatic Bladder
Overflow incontinence
Atonic Bladder
Hypernatremia (NaCl Excess)
Increased ECF Volume, Decreased hematocrit
Primary aldosteronism, Cushing’s
(Hyperosmotic Volume Expansion)
Hypernatremia (H2O loss)
Decreased ECF Volume, Increased hematocrit
Diabetes, Sweating
(Hyperosmotic Volume Contraction)
Hyponatremia (Excess H2O)
Increased ECF, Decreased Hematocrit
SIADH
(Hypo-Osmotic Volume Expansion)
Hyponatremia (NaCl loss)
Decreased ECF, Increased Hematocrit
Adrenal Insufficiency (decreased aldosterone)
(Hypo-Osmotic Volume Contraction)
Iso-Osmotic Volume Contraction
Hemorrhage
Decreased ECF volume, no other changes
Iso-Osmotic Volume Expansion
Administration of 0.9% Saline
Increased ECF, no other changes
