Acid-Base Balance Flashcards
5 Sources of free hydrogen ion production
- Complete Metabolism of Carbs
- Protein metabolism
- Incomplete metabolism of Carbs (Anaerobic metabolism)
- Cell lysis
- Incomplete oxidation of fatty acids
pH is normal when acid to base ratio is…
1:20
base exists as bicarbonate (HCO3)
acid exists as carbonic acid (H2CO3)
Regulatory Mechanisms of pH
Chemical Buffers > Respiratory control of carbon dioxide> Renal regulation of bicarbonate
Chemical Buffers
- like sponges
- Immediate action
- ongoing (always happening)
Respiratory control of carbon dioxide
Breathing faster or slower
Renal regulation of bicarbonate
Strongest line of defense 24-28 hours to kick in
pH
7.35 -7.45
PaCO2
35-45 mmHg
PaO2
80-100 mmHg
<80=hypoxic
HCO3-
22-26 mEq/L
Respiratory Acidosis
- Decreased pH
- Normal bicarbonate
- Increased CO2
Examples of Repiratory Acidosis
- COPD
- Choking r/t hypoventilation
- Status Asthmaticus
- Narcotic use r/t hypoventilation
Respiratory Alkalosis
- increased pH
- normal bicarbonate
- Decreased CO2
Examples of Respiratory Alkalosis
- hyperventilation
- anxiety
- high fever
- some head injuries
Metabolic Acidosis
- decreased pH
- decreased bicarbonate
- normal CO2
Examples of Metabolic Acidosis
- DKA
- lactic acidosis
- Diarrhea
- Renal insufficiency
Metabolic Alkalosis
- increased pH
- Increased bicarbonate
- normal CO2
Examples of Metabolic Alkalosis
- vomiting
- NG suction
- low serum K+