Acid-Base Balance Flashcards

1
Q

5 Sources of free hydrogen ion production

A
  1. Complete Metabolism of Carbs
  2. Protein metabolism
  3. Incomplete metabolism of Carbs (Anaerobic metabolism)
  4. Cell lysis
  5. Incomplete oxidation of fatty acids
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2
Q

pH is normal when acid to base ratio is…

A

1:20
base exists as bicarbonate (HCO3)
acid exists as carbonic acid (H2CO3)

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3
Q

Regulatory Mechanisms of pH

A

Chemical Buffers > Respiratory control of carbon dioxide> Renal regulation of bicarbonate

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4
Q

Chemical Buffers

A
  • like sponges
  • Immediate action
  • ongoing (always happening)
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5
Q

Respiratory control of carbon dioxide

A

Breathing faster or slower

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6
Q

Renal regulation of bicarbonate

A

Strongest line of defense 24-28 hours to kick in

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7
Q

pH

A

7.35 -7.45

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8
Q

PaCO2

A

35-45 mmHg

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9
Q

PaO2

A

80-100 mmHg

<80=hypoxic

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10
Q

HCO3-

A

22-26 mEq/L

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11
Q

Respiratory Acidosis

A
  • Decreased pH
  • Normal bicarbonate
  • Increased CO2
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12
Q

Examples of Repiratory Acidosis

A
  • COPD
  • Choking r/t hypoventilation
  • Status Asthmaticus
  • Narcotic use r/t hypoventilation
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13
Q

Respiratory Alkalosis

A
  • increased pH
  • normal bicarbonate
  • Decreased CO2
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14
Q

Examples of Respiratory Alkalosis

A
  • hyperventilation
  • anxiety
  • high fever
  • some head injuries
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15
Q

Metabolic Acidosis

A
  • decreased pH
  • decreased bicarbonate
  • normal CO2
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16
Q

Examples of Metabolic Acidosis

A
  • DKA
  • lactic acidosis
  • Diarrhea
  • Renal insufficiency
17
Q

Metabolic Alkalosis

A
  • increased pH
  • Increased bicarbonate
  • normal CO2
18
Q

Examples of Metabolic Alkalosis

A
  • vomiting
  • NG suction
  • low serum K+