Acid Base

Question 1

Alpha Stat (CO2 Content same) Benefits

Answer 1

• Maintain pH (H+) difference across Cell membrane
• Maintain +:- ratio of protein
• Proper enzyme function regardless of temp
• Maintain constant charge on alpha-imidazole side chain
• Cell Maintains electroneutrality
• AUTO-REGULATION Maintained
• *Maldistribution Ischemia Injury**

Question 2

pH Stat

Answer 2

• Ratio of Unprotonated Imidazole to H+ changes
• More acidic blood (added CO2)
• Acidity alters metabolism
• pH (H+) gradient changes across cell membrane
• CO2 influences flow regulation (NO AUTOREGULATION)
• Acidity shifts oxy-hemo curve right; offsetting hypothermias shift left
• *Embolic/ Hi Pressure/ Edema Injury**

Question 3

Alpha Value

Answer 3

Ratio of Unprotonated Imidazole to H+