Ach Actions Flashcards
1
Q
Inhibit Ach uptake
A
Hemicholinium
2
Q
Inhibit release of Ach
A
Botulin toxin
3
Q
Muscarin agonist
Direct-acting cholinomimetics
(Receptor N and M level)
A
Ach
Bethanechol (ileus, urinary retantion)
Methacoline
Pilocarpine (xerostomia, glaucoma)
4
Q
Acetylcholinesterase inhibitor
Indirect acting cholinomimetics
A
Edrophonium (Dx. Myasthenia gravis)
Physostigmine (antidote in atropine overdose)
neostigmine, pyridostigmine (myasthenia gravis)
Donepezil (Alzheimer)
Organophosphate (malathion, parathion)
5
Q
Management of toxicity of AchE inhibitors
A
Atropin (blocks m receptors)
Pralidoxin (regenerates AchE)
6
Q
M blockers
A
Atropine Ipratropium (asthma) Scopolamine (motion sickness) Benztropine ( Parkinson) Oxybutynin (overactive bladder)
7
Q
Ganglion blocking agents
Prevent baroreceptor reflex changes in HR
A
Hexamethonium
Mecamylamine