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Enfermedades inflamatorias > Acetato de Metilprednisolona > Flashcards

Acetato de Metilprednisolona Flashcards

1
Q

Mecanismo de acción

A

Síntesis de macrocortina, inhibí la actividad de fosfolipasa A2 y por ende se disminuye la liberación de acido araquidónico

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2
Q

Indicaciones clínicas

A

Asma

Gota aguda

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3
Q

Biodisponibilidad

A

92%

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4
Q

Unión a proteínas plasmáticas

A

70%

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5
Q

Vía de Administración

A

Intramuscular

Intravenosa

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6
Q

Volumen aparente de distribución

A

0.4 l/kg

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7
Q

Excreción

A

Renal

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8
Q

Vida media de eliminación

A

2 - 3 hrs

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9
Q

Metabolismo

A

Hepático a metabolitos activos

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10
Q

Reacciones Adversas

A

Nerviosismo, insomnio, dolor muscular, sangrado gastrointestinal

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Enfermedades inflamatorias (11 decks)

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