ACEIs

Question 1

MOA
1. Sulfur hydral containg
Captopril - zofinopril

2. Sulfur hydral non containging
   Eanalpril - isinopril - benzylpril

Answer 1

1. • ACEIs
2. ⬇️ aldsrone
3. ⬇️ apoptosis
4. Direct V.D action
5. ⬆️ bradykinine&raquo_space; VD

Question 2

Effects in CVS

Answer 2

1. ⬇️BP&raquo_space; rest baro r
   &raquo_space; + vegus berve&raquo_space; bradycardia
   &raquo_space; direct VD
2. ⬆️⬆️COP for CHF pt only bcuz it ⬇️ artral resistance

Question 3

Uses»

Answer 3

1. HTN
2. CHF
3. Post MI
4. DM nephropathy
   ⭐️DM + HTN > best drugs

Question 4

S/E

Answer 4

C cough
A anigo edema
P protein urea 
T tast change
O ortho static hypertension 
P pregnancy teratogencity
R rash
I ⬆️k
L leukpenia

Question 5

C/I

Answer 5

1. Angi edema
2. Renal failure
3. Pregnancy
4. Hyperkalemia
5. Leukepenia