ACE 2013 10B Flashcards
How do NSAIDs affect the kidneys?
They inhibit production of prostaglandins which cause afferent arterial vasodilation which can cause acute renal failure
Which is a side effect seen with NSAIDs: obstructive uropathy, elevated BP, renal vasodilation, hypokalemia
Elevated BP - thought to be secondary to Na retention and volume expansion
What is the treatment for neurogenic diabetes insipidus?
Infusion of isotonic fluids (use hypotonic fluids if plasma osmolarity reaches 290 mOsm/L or higher) + desmopressin (DDAVP)
What is the treatment for nephrogenic diabetes insipidus?
Infusion of isotonic or hypotonic solutions + chlorpropamide or clofibrate (potentiate effects of arginine vasopressin on renal tubules)
What is the treatment for nephrogenic diabetes insipidus?
Infusion of isotonic or hypotonic solutions + chlorpropamide or clofibrate (potentiate effects of arginine vasopressin on renal tubules)
Which of the following increases risk of postop apnea in a ex-32 weeker: post-conceptual age 60 weeks, intraop caffeine, anemia, hx of necrotizing enterocolitis
Anemia
What is the Modified Aldrete Scoring System and what does it consist of?
PACU discharge criteria
Consists of Respiration, oximetry, BP, level of consciousness, and activity
What is the Post-Anesthetic Discharge Scoring System and what does it consist of?
PACU discharge criteria
Consists of pain, bleeding, nausea, CV changes, activity
What is the Post-Anesthetic Discharge Scoring System and what does it consist of?
PACU discharge criteria
Consists of pain, bleeding, nausea, CV changes, activity
Which of the following is an absolute contraindication for ECT: pregnancy, AICD, pheochromocytoma, neuroleptic malignant syndrome
Pheochromocytoma
Which of the following is an absolute contraindication for ECT: pregnancy, AICD, pheochromocytoma, neuroleptic malignant syndrome
Pheochromocytoma
What level are the cardiac accelerator fibers located?
Sympathetic fibers from T1-T4
Why might you see bradycardia following spinal anesthesia to T10?
Reverse Bainbridge reflex: normally, increased venous return causes increased HR (via SNS and inhibition of vagal outflow); this is the opposite where decreased venous return (from spinal) causes bradycardia
Why might you see bradycardia following spinal anesthesia to T10?
Reverse Bainbridge reflex: normally, increased venous return causes increased HR (via SNS and inhibition of vagal outflow); this is the opposite where decreased venous return (from spinal) causes bradycardia
Name some medications that are given intraoperatively that should be avoided in patients with Parkinson Disease
Promezathine, droperidol, metoclopramide (any medication that decreases the effects of dopamine)
How long after cosmetic liposuction via the tumescent technique do you expect peak serum levels of lidocaine?
12-14 hours after injection
How long after cosmetic liposuction via the tumescent technique do you expect peak serum levels of lidocaine?
12-14 hours after injection
What do you worry about in a neonate with generalized cyanosis and a concave abdomen?
Congenital diaphragmatic hernia
What congenital abnormalities are most commonly associated with congenital diaphragmatic hernias?
CVS (50%): ASD/VSD, ToF, Coarctation
GI (40%): malrotation
CNS (20%): spina bifida, hydrocephalus, microcephaly
What side effects do you worry about in patients taking cyclosporine?
Acute kidney injury
What side effects do you worry about in patients taking bleomycin?
Pulmonary fibrosis
What side effects do you worry about in patients taking bleomycin?
Pulmonary fibrosis
What are the classic characteristics of obesity hypoventilation syndrome?
- Obesity (BMI >30)
- Daytime awake hypercapnia and hypoxia
- Sleep-disordered breathing without another known cause
What are the classic characteristics of obesity hypoventilation syndrome?
- Obesity (BMI >30)
- Daytime awake hypercapnia and hypoxia
- Sleep-disordered breathing without another known cause
What medications are capable of producing burst suppression?
Volatile anesthetic gases (~2 MAC), etomidate, propofol, and barbiturates
Which is least likely to cause airway obstruction 1 hour after total thyroidectomy: neck hematoma, recurrent laryngeal nerve injury, tracheomalacia, hypercalcemia
Hypercalcemia (total thyroidectomies lead to hypocalcemia from parathyroid removal)
Which is least likely to cause airway obstruction 1 hour after total thyroidectomy: neck hematoma, recurrent laryngeal nerve injury, tracheomalacia, hypercalcemia
Hypercalcemia (total thyroidectomies lead to hypocalcemia from parathyroid removal)
What do you worry about in chronic methamphetamine users?
- Depletion of neurotransmitters (NE and epi) - hypotension
2. Cardiomyopathy (40% of patients)
PEEP of 10 cm H2O will decrease which of the following: FRC, airway resistance, dead space, arterial oxygen sat
Airway resistance (from increase in lung volume)
What does the addition of sodium bicarbonate to lidocaine do?
Decreases pain on subcutaneous infiltration; although there are more non-ionized forms from the decreased pH, studies have not shown decreases in onset time or block intensity
Which is most associated with increased risk of worsening neurologic function in MS: epidural, peripheral nerve block, GA, hyperthermia
Hyperthermia - Uhthoff phenomenon (body temp elevation of 0.5C or more will exacerbate MS symptoms)
Which is most associated with increased risk of worsening neurologic function in MS: epidural, peripheral nerve block, GA, hyperthermia
Hyperthermia - Uhthoff phenomenon (body temp elevation of 0.5C or more will exacerbate MS symptoms)
What are some ECG findings for hypercalcemia? Hypocalcemia?
Hyper: shortened PR and QTc intervals
Hypo: prolonged QTc interval
What medication should you try to avoid in hypercalcemia?
Thiazide diurectics - they will induce hypercalcemia
What are common findings for critical illness polyneuropathy?
Respiratory muscle weakness (slow to wean off vent) and distal weaknesses (mostly lower extremity); you do NOT see cranial nerve or facial abnormalities