ACCS Flashcards
What type of hypersensitvity reaction is Anaphylaxis
Type 1
igE- histamine, mast cells, basophils
sx of anaphylaxis
- skin flushing
- hives/urticaria- pruritis
- Swelling of throat/mouth- wheeze, SOB, dyspnoea
- N+V, diarrhoea, abdo pain
- confusion, headache, anxiety
signs of anaphylaxis
- hypotension
- wheeze
- weak, rapid pulse
- pallor
immediate management of anaphylaxis
- ABCDE A- establish airway B- high flow O2 C- pulse ox, ECG, BP , IV fluid bolus (500ml adults, 10ml/kg children) D- GCS monitoring
- if stridor- adrenaline 5mL of 1mg/mL nebs
- if persistent bronchospasm- neb salbutamol, ipratropium
- remove trigger eg stop infusion
- *- sitting position if conscious (for breathing)
- *- if pregnant- lie on L (venous return)
IM 1:1000 (1g in 1000ml) Adrenaline
- <6m 100-150mcg
- 6m-6y 150 mcg
- 6y-12y 300mcg
- > 12yo/post pubescent 500mcg
- -> repeat after 5 min no response
- cetrizine, ***chlorphenamine
- after 2 IM injections prepare the infusion and follow refractory anaphylaxis algorithm- see other FC
what is the refractory anaphylaxis algorithm
After 2 IM injections of adrenaline with no response:
- IV fluid bolus
- continue IMs every 5 mins until infusion up and running
INFUSION
- 1mg (1mL of 1mg/ml– 1g:1000ml) adrenaline in 100ml 0.9% NaCl
- start at 0.5-1mL/kg/hour in both adults and children
- give in dedicated line and not on same side as BP cuff
- consider vasopressin
- consider glucagon in betablocker pts (reverses)
- take sample of mast cell tryptase
- high flow O2, aim spO2 94-98%
- monitor HR, BP, sats, ECG
NB- hgih BP means adrenaline overdose
Immediate management of chest pain pt
MONA
- IV opioids- Morphine
- O2, sats
- GTN- buccal or SL
- Aspirin 300mg
- hyperglycaemia- if >11mol/L- give insulin (5-10u actrapid)
Management of confirmed STEMI
- MONA plus
- PCI within 12 hours of sx onset
- if PCI not available within 120mins of diagnosis- thrombolyse (alteplase)
- if pt is in shock/has CI to fibrinolysis- PCI
- if fibrinolysis fails- PCI
- if thrombolysis is successful- -revasc via angioplasty within 24 hours
Also give:
- clopi/ticagrelor/prasugrel
- ACEI
- betablocker
- heparin
Management of NSTEMI
MONA plus
- clopidogrel/ticagrelor/prasugrel
- angio, PCI
- fondaparinux
- herparin if renally impaired/low body wt
tx bradycardia with pulse
Unstable (HF, shock, MI)
- atropine 500mcg
- repeat to 3mg
- (or isoprenaline, adrenaline, transcutaneous pacing)
Stable, with hx of asystole, mobitz II/complete block, vent pause >3s
- atropine 500mcg
- up to 3mg
- (or isoprenaline, adrenaline, transcutaneous pacing)
If stable- observe
tx tachycardia with pulse
Unstable
- 3x DC shock
- amiodarone 300mg IV over 10-20mins
- repeat shock
- amiodarone 900mg over 24hours
Stable:
Broad, regular QRS
- VT- amiodarone 300mg IV, then 900mg over 24hours
- SVT with BBB- adenosine 6mg bolus, then 12mg, then 12mg again
Broad irregular- get help
- AF with BBB- BB/diltiazem, digoxin/amiodarone if in HF
- **- pre-excited AF- amiodarone
- polymorphic VT (torsades de pointes)- Mg 2g 10m
Narrow, regular
- vagal manouvres
- adenosine 6mg bolus, 12mg, 12mg
- if not resolved ?atrial flutter–> beta blocker
Narrow, irregular
- probably AF- BB/diltiazem, amiodarone/digoxin if in HF
immediate management of pt without a pulse (cardiac arrest)
- shake their shouder, shout at them
- trap squeeze
- shout for help
ABCDE
- head tilt/chin lift
- pulse palpation– no pulse- move to ALS
- listen, feel, look for breathing for 10s
- commence CPR 30:2
- attch defib pads (one on upper R side below collar bone, other on L side below axilla
- pause CPR to analyse rhythm
is it shockable or not?
What are the shockable rhythms
- Pulseless VT- wide QRS, regular
- Vent fib- wide QRS, irregular, chaotic, deflections vary in amplitude
Management of shockable rhythms
- resume CPR immediately once trace is read
- charge defib, 150J
- when shocking- remove any O2 delivery devices/masks
- everyone stand clear
- 1 shock
- resume CPR for 2 mins
- if still shockable, give 2nd shock
- continue CPR for 2 mins
- if still shcokable, give 3rd shock
After 3rd shock, give:
- adrenaline 1mg IV (10ml of 1:10,000)
- Amiodarone 300mg IV
- continue shocks and CPR, giving the same dose of adrenaline and amiodarone after 5th, 7th, 9th, 11th shocks
- if non-shockable rhythms appear, swithc to that algorithm
- if organised electrcal activity is seen, commence post resus care
what are the non-shockable rhythms
- asytole
- pulseless electrical activity (PEA)
management of non-shockable rhythma
1st rhythm check:
- if asystole/PEA, ***resume CPR
- if returns to spontaneous circulation (pulse) or switches to shockable rhythm, switch to appropriate algorithm/care
- after 2 mins of CPR, give IV adrenaline 1mg (10ml of 1:10,000)
- resume CPR for 2 mins
- 2nd rhythm check
- resume CPR if still asystole/PEA for 2 mins
- 3rd rhythm check
- give IV adrenaline 1mg
- continue givign adrenaline after alternative rhythm checks (5th,7th,9th)
- if shockable rhythms is identified, switch to other algorithm, but continue giving adrenaline after alternative rhythm checks
what are the reversible causes of cardiac arrest
6 Hs, 5Ts- someone should be investigating/ruling out and treating these whilst ALS is occurring
- Hypovolaemia
- *- Hypoxia
- Hydrogen (acidosis)- tx cause/bicarb
- Hypo/hyperkalaemia
- *- Hypoglycaemia
- Hypothermia
- *- Toxins
- *- Tamponade - paricardiocentesis
- Tension PTX- needle compression, chets tube
- Thrombosis (MI, PE)
- Trauma
sx of acute hypertensive crisis
- haemorrhage generally HEART- - aortic dissection- tearing chest / back pain - MI BRAIN **- confusion (encephalothpathy) - SAH - changes in vision **RESP- acute pulmonary oedema **RENAL- haematuria, oliguria