Abx ADEs Flashcards
1
Q
Penicillins ADEs?
A
- Allergy/ hypersensitivity (anaphylaxis, SJS, TEN)
- GI (n/v)
- Neurotoxicity
2
Q
Cephalosporins ADEs?
A
- Hypersensitivity
- GI (n/v/d)
- CDAD* (higher risk)
3
Q
Carbapenems ADEs?
A
- Hypersensitivity
- GI s/sx (n/v/d)
- Neurotoxicity
4
Q
Vancomycin ADEs?
A
- Nephrotoxicity
- Ototoxicity
- Red man syndrome
5
Q
Tetracyclines ADEs?
A
- GI discomfort
- Primary dentition (discoloration and hypoplasia of teeth), stunting of growth
- Hepatotoxicity
- Phototoxicity
- Vestibular dysfunction
- Renal SEs (esp w renal disease)
6
Q
AGs ADEs?
A
- Ototoxicity
- Nephrotoxicity
- Neuromuscular paralysis (NOT for myasthenia gravis)
- Hypersensitivity
- NOT for renal impairment/ hearing defects
7
Q
Macrolides ADEs?
A
- GI discomfort
- Hepatotoxicity
- Ototoxicity
- Prolonged QT interval
8
Q
Clindamycin ADEs?
A
- Esophageal irritation (take with full glass of water)
- GI (d/n/v)
- Skin rashes
- CDAD* (higher risk)
9
Q
FQs ADEs?
A
- GI (n/v/d)
- Dysglycemia
- Aortic ruptures/ dissections
- CDAD* (higher risk esp cipro)
- Headache, dizziness
- Phototoxicity
- Tendonitis, tendon rupture
- NOT for < 18y/o (joint problems)
- Prolong QT interval
- Peripheral neuropathy (systemic use)
10
Q
Co-trimoxazole ADEs?
A
- Crystalluria
- Hypersensitivity
- Haemopoietic disturbances
- Kernicterus
11
Q
Metronidazole ADEs?
A
- GI
- Unpleasant metallic taste
- Oral moniliasis (yeast infection)
12
Q
A
