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Therapeutics III > Abx > Flashcards

Abx Flashcards

1
Q

Cell wall inhibitors

A 
Penicillins
Cephalosporin
Monobactam
Carbapenems
Glycopeptides
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2
Q

Cell wall inhibitor S vs C

A

Cidal

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3
Q

Cell wall inhibitors PD

A

TD

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4
Q

Penicillin common uses

A

RTI, STI, Skin, UTI, IA, blood, meningitis

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5
Q

Penicillin spectrum

A

Gram positive

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6
Q

Amoxicillin spectrum

A

Gram positive/negative

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7
Q

Piperacillin/Tazobactam spectrum

A

Gram +, Gram -, pseudomonas, anaerobes

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8
Q

Augmentin/ Unasyn spectrum

A

Gram +, Gram-, anaerobes

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9
Q

1 gen cephalosporin spectrum

A

Gram +, some gram -

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10
Q

2nd gen cephalosporin spectrum

A

Gram +, Gram -

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11
Q

3rd gen cephalosporin spectrum

A

Gram +, Gram-,

Ceftazidime- pseudomonas

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12
Q

4th gen ceph spectrum

A

Gram +, Gram -, pseudomonas

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13
Q

Carbapenems spectrum

A

Gram +, Gram -, pseudomonas (except erta), anaerobes

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14
Q

Aztreonam spectrum

A

Gram -, pseudomonas

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15
Q

Fluoroquinolones spectrum

A

Some gram +, gram -

Moxi- anaerobes and atypicals

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16
Q

aminoglycosides spectrum

A

Gram -, pseudomonas

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17
Q

Macrolides spectrum

A

Gram +, Gram -, atypicals

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18
Q

tetracyclines spectrum

A

MRSA- doxycycline
Gram +, some gram -
Atypicals

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19
Q

Clindamycin spectrum

A

MRSA

Gram +

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20
Q

Vancomycin spectrum

A

MRSA

Gram +

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21
Q

Daptomycin spectrum

A

MRSA,

Gram +

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22
Q

Linezolid spectrum

A

MRSA

Gram +

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23
Q

Fosfomycin spectrum

A

Gram +, Gram -, pseudomonas

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24
Q

Colistin spectrum

A

Gram -, pseudomonas

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25
Tigecycline spectrum
MRSA, gram +, gram -, anaerobes, atypicals
26
Cephalosporins common uses
RTI, UTI, STI, skin, blood, meningitis
27
Monobactams uses
Only in severe beta-lactam allergies
28
Carbapenems uses
Reserved for serious, life-threatening infections
29
Glycopeptides uses
MRSA
30
Lipopeptides uses
MRSA
31
Polymyxins uses
Multi-drug resistant
32
Membrane inhibitors
Lipopeptids- Daptomycin | Cationic proteins- Polymyxins
33
Membrane inhibitors S vs C
Cidal
34
Membrane inhibitors PD
CD
35
DNAi
Fluoroquinolones
36
DNAi S vs C
Cidal
37
DNAi PD
CD
38
Fluoroquinolones common uses
RTI, STI, Skin, UTI
39
PI 50s
Macrolides (Erythromycin, Azithromycin) Lincosamides (clindamycin) Chloramphenicol
40
PI 50s S vs C
Static
41
PI 50s PD
TD
42
Macrolides common uses
RTI, STI, skin | Gram +, atypicals
43
Lincosamides common uses
Beta lactam allergy | Gram -, anaerobes
44
Chloramphenicol uses
Toxic:reserved
45
MAOI
Linezolid
46
MAOI S vs C
S
47
MAOI PD
TD
48
MAOI common uses
MRSA
49
PI 30s
Aminoglycosides | Tetracyclines
50
Aminoglycosides S vs C
C
51
Aminoglycosides PD
CD
52
Aminoglycosides common uses
Gram - | Serious hospital; synergy
53
Tetracyclines S vs C
S
54
tetracyclines PD
TD
55
Tetracyclines common uses
Broad spectrum, atypicals RTI, tick-borne MDRO (Tige)
56
Sulfonamides S vs C
C
57
Sulfonamides PD
TD
58
Sulfonamides common uses
UTI, PJP, Toxo
59
Nitrofurantoin S vs C
C
60
Nitrofurantoin PD
TD
61
Nitrofurantoin uses
e.coli UTI
62
Beta lactams common AE
GI, rash, allergy
63
Vancomycin common AE
Nephrotoxicity, ototoxicity, Red-man syndrome
64
Daptomycin common AE
Myopathy
65
Polymyxins common AE
Nephrotoxicity, neurotoxicity
66
Fluoroquinolones commone AE
GI, CNS stimulation, photosensitivity Warnings: Cartilage malformation, tendonitis/rupture, peripheral neuropathy, prolonged QTc, hypoglycemia, mental health, aortic aneurysm
67
Macrolides common AE
``` GI QTc prolongation (DDI) ```
68
Lincosamides AE
GI
69
Chloramphenicol AE
Anemia, b.m suppression, Gray Baby syndrome
70
Oxazolidinones AE
(linezolid) | GI, CNS, myelosuppression
71
Aminoglycosides AE
Nephrotoxicity, ototoxicity
72
Tetracyclines AE
GI, rash/allergy, photosensitivity, superinfection | Do not use in children (teeth discoloration)
73
Sulfonamides AE
GI, Rash, photosensitivity,myelosuppression | Do not use in 3rd trimester or with newborns
74
Nitrofurantoin AE
GI, rash, pulmonary

Therapeutics III (7 decks)

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