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Therapeutics III > Abx > Flashcards

Abx Flashcards

1
Q

Cell wall inhibitors

A 
Penicillins
Cephalosporin
Monobactam
Carbapenems
Glycopeptides
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2
Q

Cell wall inhibitor S vs C

A

Cidal

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3
Q

Cell wall inhibitors PD

A

TD

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4
Q

Penicillin common uses

A

RTI, STI, Skin, UTI, IA, blood, meningitis

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5
Q

Penicillin spectrum

A

Gram positive

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6
Q

Amoxicillin spectrum

A

Gram positive/negative

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7
Q

Piperacillin/Tazobactam spectrum

A

Gram +, Gram -, pseudomonas, anaerobes

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8
Q

Augmentin/ Unasyn spectrum

A

Gram +, Gram-, anaerobes

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9
Q

1 gen cephalosporin spectrum

A

Gram +, some gram -

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10
Q

2nd gen cephalosporin spectrum

A

Gram +, Gram -

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11
Q

3rd gen cephalosporin spectrum

A

Gram +, Gram-,

Ceftazidime- pseudomonas

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12
Q

4th gen ceph spectrum

A

Gram +, Gram -, pseudomonas

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13
Q

Carbapenems spectrum

A

Gram +, Gram -, pseudomonas (except erta), anaerobes

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14
Q

Aztreonam spectrum

A

Gram -, pseudomonas

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15
Q

Fluoroquinolones spectrum

A

Some gram +, gram -

Moxi- anaerobes and atypicals

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16
Q

aminoglycosides spectrum

A

Gram -, pseudomonas

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17
Q

Macrolides spectrum

A

Gram +, Gram -, atypicals

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18
Q

tetracyclines spectrum

A

MRSA- doxycycline
Gram +, some gram -
Atypicals

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19
Q

Clindamycin spectrum

A

MRSA

Gram +

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20
Q

Vancomycin spectrum

A

MRSA

Gram +

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21
Q

Daptomycin spectrum

A

MRSA,

Gram +

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22
Q

Linezolid spectrum

A

MRSA

Gram +

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23
Q

Fosfomycin spectrum

A

Gram +, Gram -, pseudomonas

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24
Q

Colistin spectrum

A

Gram -, pseudomonas

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25
Q

Tigecycline spectrum

A

MRSA, gram +, gram -, anaerobes, atypicals

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26
Q

Cephalosporins common uses

A

RTI, UTI, STI, skin, blood, meningitis

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27
Q

Monobactams uses

A

Only in severe beta-lactam allergies

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28
Q

Carbapenems uses

A

Reserved for serious, life-threatening infections

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29
Q

Glycopeptides uses

A

MRSA

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30
Q

Lipopeptides uses

A

MRSA

31
Q

Polymyxins uses

A

Multi-drug resistant

32
Q

Membrane inhibitors

A

Lipopeptids- Daptomycin

Cationic proteins- Polymyxins

33
Q

Membrane inhibitors S vs C

A

Cidal

34
Q

Membrane inhibitors PD

A

CD

35
Q

DNAi

A

Fluoroquinolones

36
Q

DNAi S vs C

A

Cidal

37
Q

DNAi PD

A

CD

38
Q

Fluoroquinolones common uses

A

RTI, STI, Skin, UTI

39
Q

PI 50s

A

Macrolides (Erythromycin, Azithromycin)
Lincosamides (clindamycin)
Chloramphenicol

40
Q

PI 50s S vs C

A

Static

41
Q

PI 50s PD

A

TD

42
Q

Macrolides common uses

A

RTI, STI, skin

Gram +, atypicals

43
Q

Lincosamides common uses

A

Beta lactam allergy

Gram -, anaerobes

44
Q

Chloramphenicol uses

A

Toxic:reserved

45
Q

MAOI

A

Linezolid

46
Q

MAOI S vs C

A

S

47
Q

MAOI PD

A

TD

48
Q

MAOI common uses

A

MRSA

49
Q

PI 30s

A

Aminoglycosides

Tetracyclines

50
Q

Aminoglycosides S vs C

A

C

51
Q

Aminoglycosides PD

A

CD

52
Q

Aminoglycosides common uses

A

Gram -

Serious hospital; synergy

53
Q

Tetracyclines S vs C

A

S

54
Q

tetracyclines PD

A

TD

55
Q

Tetracyclines common uses

A

Broad spectrum, atypicals
RTI, tick-borne
MDRO (Tige)

56
Q

Sulfonamides S vs C

A

C

57
Q

Sulfonamides PD

A

TD

58
Q

Sulfonamides common uses

A

UTI, PJP, Toxo

59
Q

Nitrofurantoin S vs C

A

C

60
Q

Nitrofurantoin PD

A

TD

61
Q

Nitrofurantoin uses

A

e.coli UTI

62
Q

Beta lactams common AE

A

GI, rash, allergy

63
Q

Vancomycin common AE

A

Nephrotoxicity, ototoxicity, Red-man syndrome

64
Q

Daptomycin common AE

A

Myopathy

65
Q

Polymyxins common AE

A

Nephrotoxicity, neurotoxicity

66
Q

Fluoroquinolones commone AE

A

GI, CNS stimulation, photosensitivity
Warnings: Cartilage malformation, tendonitis/rupture, peripheral neuropathy, prolonged QTc, hypoglycemia, mental health, aortic aneurysm

67
Q

Macrolides common AE

A 
GI
QTc prolongation (DDI)
68
Q

Lincosamides AE

A

GI

69
Q

Chloramphenicol AE

A

Anemia, b.m suppression, Gray Baby syndrome

70
Q

Oxazolidinones AE

A

(linezolid)

GI, CNS, myelosuppression

71
Q

Aminoglycosides AE

A

Nephrotoxicity, ototoxicity

72
Q

Tetracyclines AE

A

GI, rash/allergy, photosensitivity, superinfection

Do not use in children (teeth discoloration)

73
Q

Sulfonamides AE

A

GI, Rash, photosensitivity,myelosuppression

Do not use in 3rd trimester or with newborns

74
Q

Nitrofurantoin AE

A

GI, rash, pulmonary

Therapeutics III (7 decks)

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