ABX

Question 0

Inhibition of nucleic acid synthesis ABX?

Answer 0

Quinolones - coiling- ciprofloxacin (epilepsy), levofloxacin
Metronidazole - intermedials - anaerobes, clostridia, giardia lamblia
rifampicin - rna polymerase inhibitor - orange secretions

Question 1

Cell wall disruption ABX?

Answer 1

beta lactams - Penicillin (streptococcus), flucloxicillin (straphylcoccus), benzylpenicillin (meningitis and cellulitis), amoxicillin
cephalosporins (cefalexin)
carbapenems
glycopeptides -vancomycin causes red man syndrome

Question 2

protein synthesis inhibitors ABX?`

Answer 2

Tetracyclines - stains teeth and bones
Aminoglycosides - o2 dependent eg pseudomonas - gentamicin - ototoxic and nephrotoxic
chloramphenicol - ear or eye
macrolides - penicilin allergy - clarithromycin, erythromycin

Question 3

antimetbolite abx?

Answer 3

sulphonamides - folate synthelase

trimethoprim - folate reductase - kidney infections

Question 4

abx for mrsa (straph aureas)

Answer 4

linezolid

Question 5

pseudemonas abx?

Answer 5

meropenem